Factores de crecimiento implicados en la regeneración ósea y la regeneración tisular guiada. Revisión de la literatura
- A. L. Bujaldón Daza
- F.M. Rodríguez Escudero
- P. Lázaro Calvo
- A. Bascones Martínez
ISSN: 1699-6585
Year of publication: 1997
Volume: 9
Issue: 3
Pages: 133-138
Type: Article
More publications in: Avances en periodoncia e implantología oral
Abstract
This review will discuss the use of growth factors in guided tissue regeneration and guided bone regeneration. These growth factors share several common caracteristics. They are natural cell products secreted or activated during mitosis and mainly act locally. Their production is tightly regulated in normal cells. Growth factors are multifunctional and can stimulate the cell that synthesises the molecule (autocrine stimulation) or affect nearby cells (paracrine stimulation). In periodontal regeneration, the important growth factors are: platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), insulin-like growth factor (IGF), transforming growth factor B (B- TGF) and bone morphogenetic proteins (BMPs).