¿Existe correlación clínica o radiológica a la existencia de inflamación detectable histológicamente en el disco lumbar herniado?resultados de una serie consecutiva de pacientes operados de hernia discal lumbar
- Pablo M. Munarriz
- A. Laín
- Ana María Castaño León
- Rafael Martínez Pérez
- Santiago Cepeda
- Igor Paredes
- Alfonso Lagares
ISSN: 1888-6116
Argitalpen urtea: 2014
Alea: 25
Zenbakia: 3
Orrialdeak: 121-126
Mota: Artikulua
Beste argitalpen batzuk: Trauma
Laburpena
Objective: To establish the clinical relevance of the histological evidence of inflammatory cell infiltrates in surgical samples of operated lumbar disc hernia. Material and method: Surgical samples, clinical, and epidemiological data were obtained from 50 patients consecutively operated on of lumbar disc herniation during 2012 were obtained. Also the MR appearance as extruded or contained hernia was recorded. All samples were processed using hematoxilin-eosin staining and different histological parameters were determined such as the presence and quantity of chondrocytes present in the disc as a sign of disc degeneration. Results: Even though the majority of samples examined showed signs of disc degeneration, such as the presence of chondrocyte proliferation, the evidence of neovascularisation or inflammatory infiltrates was scarce. The presence of inflammatory infiltrates was invariably related to the presence of neovascularisation. However, the presence of inflammatory infiltrates was not related to any radiological or clinical variable. Conclusion: There is no relation between the presence of inflammatory infiltrates and the clinical data registered. The presence of histological evidence of inflammation in herniated lumbar disc tissue is not related to disc degeneration or the presence of pain.