Physical activity levels are low in patients with pulmonary hypertension

  1. Quezada-Loaiza, Carlos A. 4
  2. Flox-Camacho, Angela 3
  3. Escribano-Subías, Pilar 39
  4. Santos-Lozano, Alejandro 12
  5. Fiuza-Luces, Carmen 1
  6. Alejo, Lidia B. 16
  7. Sanz-Ayán, Paz 33
  8. Ruiz-Casado, Ana 5
  9. Morán, María 17
  10. González-Saiz, Laura 1
  11. Lucia, Alejandro 168
  1. 1 Instituto de Investigación Sanitaria Hospital 12 de Octubre
    info

    Instituto de Investigación Sanitaria Hospital 12 de Octubre

    Madrid, España

  2. 2 Universidad Europea Miguel de Cervantes
    info

    Universidad Europea Miguel de Cervantes

    Valladolid, España

    ROR https://ror.org/02p350r61

  3. 3 Hospital Universitario 12 de Octubre
    info

    Hospital Universitario 12 de Octubre

    Madrid, España

    ROR https://ror.org/00qyh5r35

  4. 4 Hospital Ramón y Cajal
    info

    Hospital Ramón y Cajal

    Madrid, España

    ROR https://ror.org/050eq1942

  5. 5 Hospital Universitario Puerta de Hierro
    info

    Hospital Universitario Puerta de Hierro

    Madrid, España

    ROR https://ror.org/01e57nb43

  6. 6 Universidad Europea de Madrid
    info

    Universidad Europea de Madrid

    Madrid, España

    ROR https://ror.org/04dp46240

  7. 7 Centro de Investigación Biomédica en Red sobre Enfermedades Raras
    info

    Centro de Investigación Biomédica en Red sobre Enfermedades Raras

    Madrid, España

    ROR https://ror.org/01ygm5w19

  8. 8 Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable
    info

    Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable

    Madrid, España

  9. 9 Instituto de Salud Carlos III
    info

    Instituto de Salud Carlos III

    Madrid, España

    ROR https://ror.org/00ca2c886

Revista:
Annals of Translational Medicine

ISSN: 2305-5839 2305-5847

Año de publicación: 2018

Volumen: 6

Número: 11

Páginas: 205-205

Tipo: Artículo

DOI: 10.21037/ATM.2018.05.37 GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Annals of Translational Medicine

Resumen

Background: Pulmonary hypertension (PH) leads to exercise capacity impairment, but limited data are available on the objective evaluation of physical activity (PA) levels in these patients.Methods: We assessed PA levels using triaxial accelerometry in Spanish PH patients (n=75, 48±14 years, 65% female) and gender/age matched controls (n=107), and examined potential associations of meeting minimum international recommendations [moderate-vigorous PA (MVPA) ≥150 min/week] with survival predictors.Results: With the exception of vigorous PA (with very low values in both groups), all accelerometry data showed significant differences between patients and controls, with lower PA levels and proportion of individuals meeting minimum PA guidelines, but higher inactivity time, in the former. Notably, the odds ratio (OR) of having a “low-risk” value of 6-minute walking distance (≥464 m) or ventilatory equivalent for carbon dioxide (≤39) was higher in patients following MVPA guidelines than in their less active peers [OR =4.3, 95% confidence interval (CI), 1.6–11.6, P=0.005, and OR =4.5, 95% CI, 0.9–21.1, P=0.054].Conclusions: Daily PA is reduced in patients with PH, often to a level that may decrease their odds of survival. Efforts should be made to promote the implementation of healthy PA habits in this patient population.

Referencias bibliográficas

  • 1. Global Recommendations on Physical Activity for Health. WHO Guidelines Approved by the Guidelines Review Committee. Geneva: World Health Organization, 2010.
  • 2. Mainguy V, Provencher S, Maltais F, et al. Assessment of daily life physical activities in pulmonary arterial hypertension. PLoS One 2011;6:e27993.
  • 3. Matura LA, Shou H, Fritz JS, et al. Physical Activity and Symptoms in Pulmonary Arterial Hypertension. Chest 2016;150:46-56.
  • 4. Pugh ME, Buchowski MS, Robbins IM, et al. Physical activity limitation as measured by accelerometry in pulmonary arterial hypertension. Chest 2012;142:1391-8.
  • 5. Quezada-Loaiza CA, Flox-Camacho A, Santos-Lozano A, et al. Predictive value of NT-proBNP combined with exercise capacity variables in pulmonary artery disease: Insights from a Spanish cohort. Int J Cardiol 2015;186:32-4.
  • 6. Ruiz-Casado A, Verdugo AS, Solano MJ, et al. Objectively assessed physical activity levels in Spanish cancer survivors. Oncol Nurs Forum 2014;41:E12-20.
  • 7. Guyatt GH, Pugsley SO, Sullivan MJ, et al. Effect of encouragement on walking test performance. Thorax 1984;39:818-22.
  • 8. Santos-Lozano A, Marín PJ, Torres-Luque G, et al. Technical variability of the GT3X accelerometer. Med Eng Phys 2012;34:787-90.
  • 9. Freedson PS, Melanson E, Sirard J. Calibration of the Computer Science and Applications, Inc. accelerometer. Med Sci Sports Exerc 1998;30:777-81.
  • 10. Sanchis-Gomar F, González-Saiz L, Sanz-Ayan P, et al. Rationale and Design of a Randomized Controlled Trial Evaluating Whole Muscle Exercise Training Effects in Outpatients with Pulmonary Arterial Hypertension (WHOLEi+12). Cardiovasc Drugs Ther 2015;29:543-50.
  • 11. Mereles D, Ehlken N, Kreuscher S, et al. Exercise and respiratory training improve exercise capacity and quality of life in patients with severe chronic pulmonary hypertension. Circulation 2006;114:1482-9.
  • 12. Weinstein AA, Chin LM, Keyser RE, et al. Effect of aerobic exercise training on fatigue and physical activity in patients with pulmonary arterial hypertension. Respir Med 2013;107:778-84.