Histocompatibilidad (HLA) KIR, A, B, C, DR y DQ en el fallo reproductivo recurrente

  1. Nuñez Beltran, Maria
Supervised by:
  1. Silvia Maria Sánchez Ramón Director
  2. Miguel Fernández Arquero Director
  3. Miguel Ángel Herráiz Martínez Director

Defence university: Universidad Complutense de Madrid

Fecha de defensa: 05 November 2021

Committee:
  1. Pluvio J. Coronado Martín Chair
  2. Gloria del Mar Candelas Rodríguez Secretary
  3. Ignacio Cristobal García Committee member
  4. Eva Calabuig Muñoz Committee member
  5. José Miguel Sempere Ortells Committee member
Department:
  1. Inmunología, Oftalmología y ORL

Type: Thesis

Teseo: 157727 DIALNET

Abstract

Recurrent reproductive failure [RRF] includes two factors: recurrent spontaneous abortion [RSA] and recurrent implantation failure [RIF]. The rate of RSA in the general population is up to 1-3% and that of RIF in women who have undergone IVF is between 10-15%.To achieve a term pregnancy, there must be a certain tolerance of the embryo by the maternal immune system. Among the many etiologies known, embryo HLA recognition in the maternal environment is known as a relevant factor in RRF...