The Use of Prebiotics from Pregnancy and Its Complications: Health for Mother and Offspring—A Narrative Review

  1. García-Montero, Cielo 56
  2. Fraile-Martinez, Oscar 56
  3. Rodriguez-Martín, Sonia 57
  4. Saz, Jose V. 4
  5. Rodriguez, Rocio Aracil 123
  6. Moreno, Juan Manuel Pina 123
  7. Labarta, Javier Ruiz 123
  8. García-Honduvilla, Natalio 56
  9. Alvarez-Mon, Melchor 568
  10. Bravo, Coral 123
  11. De Leon-Luis, Juan A. 123
  12. Ortega, Miguel A. 56
  1. 1 Department of Public and Maternal and Child Health, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain
  2. 2 Department of Obstetrics and Gynecology, University Hospital Gregorio Marañón, 28009 Madrid, Spain
  3. 3 Health Research Institute Gregorio Marañón, 28009 Madrid, Spain
  4. 4 Department of Biomedicine and Biotechnology, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Alcalá de Henares, Spain
  5. 5 Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Alcalá de Henares, Spain
  6. 6 Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain
  7. 7 Service of Pediatric, Hospital Universitario Principe de Asturias, 28801 Alcalá de Henares, Spain
  8. 8 Immune System Diseases-Rheumatology and Internal Medicine Service, University Hospital Príncipe de Asturias, CIBEREHD, 28806 Alcalá de Henares, Spain
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Revista:
Foods

ISSN: 2304-8158

Año de publicación: 2023

Volumen: 12

Número: 6

Páginas: 1148

Tipo: Artículo

DOI: 10.3390/FOODS12061148 GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Foods

Resumen

Pregnancy involves a metabolic reprogramming that includes changes in the gut microbiota composition in women. Evidence shows that maternal dysbiosis is linked to neonatal dysbiosis, and this factor can determine health status in adulthood. Although there is little literature available on this topic, high heterogeneity is a limitation when examining nutritional interventions. Information has been gathered to contrast the benefits of prebiotic usage, specifically in pregnancy, in its possible complications and in newborns’ gut microbiota development. The objective pursued in this brief narrative review is to provide a clear summary of relevant content when searching with regard to the use of prebiotics in pregnancy, the effects in prenatal and postnatal periods, and to help in clinical decision-making in pregnancy management and lactation. A search has found that the nutritional status of the pregnant mother is key for the earliest microbial colonization in newborns, and thus intervention programs from pregnancy could assure better outcomes in both the mother and offspring. In this sense, prebiotics (administered to mothers who breastfeed or provided in formula milk) are feasible and cost-effective elements that can prevent allergies, colic, and other maladies in newborns.

Referencias bibliográficas

  • (2014), Srp. Arh. Celok. Lek., 142, pp. 125, 10.2298/SARH1402125P
  • Gresham, (2016), Matern. Child Nutr., 12, pp. 5, 10.1111/mcn.12142
  • Smith, (2022), Matern. Child Nutr., 18, pp. e13273, 10.1111/mcn.13273
  • Teh, K., Quek, I.P., and Tang, W.E. (2021). Postpartum dietary and physical activity-related beliefs and behaviors among women with recent gestational diabetes mellitus: A qualitative study from Singapore. BMC Pregnancy Childbirth, 21.
  • Lucas, (2014), Matern. Child Health J., 18, pp. 2465, 10.1007/s10995-014-1485-0
  • Homayouni, (2020), Curr. Diabetes Rev., 16, pp. 538
  • Venter, (2020), Pediatr. Allergy Immunol., 31, pp. 889, 10.1111/pai.13303
  • Gibson, (2017), Nat. Rev. Gastroenterol. Hepatol., 14, pp. 491, 10.1038/nrgastro.2017.75
  • Hill, (2014), Nat. Rev. Gastroenterol. Hepatol., 11, pp. 506, 10.1038/nrgastro.2014.66
  • Gibson, (1995), J. Nutr., 125, pp. 1401, 10.1093/jn/125.6.1401
  • Gibson, (2010), Food Sci. Technol. Bull. Funct. Foods, 7, pp. 1, 10.1616/1476-2137.15880
  • Davani-Davari, D., Negahdaripour, M., Karimzadeh, I., Seifan, M., Mohkam, M., Masoumi, S.J., Berenjian, A., and Ghasemi, Y. (2019). Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications. Foods, 8.
  • Swanson, (2020), Nat. Rev. Gastroenterol. Hepatol., 17, pp. 687, 10.1038/s41575-020-0344-2
  • Jarde, A., Lewis-Mikhael, A.M., Moayyedi, P., Stearns, J.C., Collins, S.M., Beyene, J., and McDonald, S.D. (2018). Pregnancy outcomes in women taking probiotics or prebiotics: A systematic review and meta-analysis. BMC Pregnancy Childbirth, 18.
  • Sheridan, (2014), Gut Microbes, 5, pp. 74, 10.4161/gmic.27252
  • Camilleri, (2021), Clin. Transl. Gastroenterol., 12, pp. e00308, 10.14309/ctg.0000000000000308
  • (2015), Nutr. Hosp., 31, pp. 3
  • Jinno, S., Toshimitsu, T., Nakamura, Y., Kubota, T., Igoshi, Y., Ozawa, N., Suzuki, S., Nakano, T., Morita, Y., and Arima, T. (2017). Maternal Prebiotic Ingestion Increased the Number of Fecal Bifidobacteria in Pregnant Women but Not in Their Neonates Aged One Month. Nutrients, 9.
  • Wibowo, (2016), Asia Pac. J. Clin. Nutr., 25, pp. S102
  • Taghizadeh, (2014), Hormones, 13, pp. 398
  • Sheyholislami, H., and Connor, K.L. (2021). Are Probiotics and Prebiotics Safe for Use during Pregnancy and Lactation? A Systematic Review and Meta-Analysis. Nutrients, 13.
  • Sohn, (2017), Semin. Fetal Neonatal Med., 22, pp. 284, 10.1016/j.siny.2017.07.002
  • Wiedmer, (2022), Front. Nutr., 9, pp. 819882, 10.3389/fnut.2022.819882
  • Zhou, (2018), Biosci. Rep., 38, pp. BSR20171234, 10.1042/BSR20171234
  • Rubini, (2022), Am. J. Obstet. Gynecol., 227, pp. 392, 10.1016/j.ajog.2022.04.013
  • Plows, J.F., Stanley, J.L., Baker, P.N., Reynolds, C.M., and Vickers, M.H. (2018). The Pathophysiology of Gestational Diabetes Mellitus. Int. J. Mol. Sci., 19.
  • Fei, (2014), Food Chem., 158, pp. 429, 10.1016/j.foodchem.2014.02.106
  • De Mendonça, E.L.S.S., Fragoso, M.B.T., de Oliveira, J.M., Xavier, J.A., Goulart, M.O.F., and de Oliveira, A.C.M. (2022). Gestational Diabetes Mellitus: The Crosslink among Inflammation, Nitroxidative Stress, Intestinal Microbiota and Alternative Therapies. Antioxidants, 11.
  • Zhou, (2021), Prim. Care Diabetes, 15, pp. 937, 10.1016/j.pcd.2021.08.005
  • Metin, (2022), Diabetes Res. Clin. Pract., 194, pp. 110162, 10.1016/j.diabres.2022.110162
  • Malinowska, (2020), Sci. Rep., 10, pp. 17796, 10.1038/s41598-020-74773-8
  • Ishimwe, (2021), Physiol. Rep., 9, pp. e14875, 10.14814/phy2.14875
  • Willmott, (2020), Front. Cell. Infect. Microbiol., 10, pp. 389, 10.3389/fcimb.2020.00389
  • Movaghar, (2022), J. Caring Sci., 11, pp. 94, 10.34172/jcs.2021.027
  • Bustamante, (2020), Folia Microbiol., 65, pp. 245, 10.1007/s12223-019-00759-3
  • Afifirad, (2022), Int. J. Clin. Pract., 2022, pp. 4774783, 10.1155/2022/4774783
  • Desai, (2021), Front. Psychiatry, 12, pp. 622181, 10.3389/fpsyt.2021.622181
  • Rackers, (2018), Psychoneuroendocrinology, 95, pp. 86, 10.1016/j.psyneuen.2018.05.020
  • Beluska-Turkan, K., Korczak, R., Hartell, B., Moskal, K., Maukonen, J., Alexander, D.E., Salem, N., Harkness, L., Ayad, W., and Szaro, J. (2019). Nutritional Gaps and Supplementation in the First 1000 Days. Nutrients, 11.
  • Firmansyah, (2016), Asia Pac. J. Clin. Nutr., 25, pp. 652
  • Zaidi, A.Z., Moore, S.E., and Okala, S.G. (2021). Impact of Maternal Nutritional Supplementation during Pregnancy and Lactation on the Infant Gut or Breastmilk Microbiota: A Systematic Review. Nutrients, 13.
  • Martin, (2016), Adv. Nutr., 7, pp. 323, 10.3945/an.115.010694
  • Ong, (2019), Cochrane Database Syst. Rev., 2019, pp. CD012473
  • Sprockett, (2018), Nat. Rev. Gastroenterol. Hepatol., 15, pp. 197, 10.1038/nrgastro.2017.173
  • Fabiano, V., Indrio, F., Verduci, E., Calcaterra, V., Pop, T.L., Mari, A., Zuccotti, G.V., Cokugras, F.C., Pettoello-Mantovani, M., and Goulet, O. (2021). Term Infant Formulas Influencing Gut Microbiota: An Overview. Nutrients, 13.
  • Davis, (2020), Dig. Dis. Sci., 65, pp. 706, 10.1007/s10620-020-06092-x
  • (2013), Ann. Nutr. Metab., 63, pp. 8, 10.1159/000354907
  • Cheng, (2021), Pediatr. Neonatol., 62, pp. 347, 10.1016/j.pedneo.2020.12.013
  • Salvini, (2011), J. Nutr., 141, pp. 1335, 10.3945/jn.110.136747
  • Burgos, (2020), Arch. Argent. Pediatr., 118, pp. 278
  • Luoto, (2013), Ann. Nutr. Metab., 63, pp. 17, 10.1159/000354896
  • Arboleya, (2018), Ann. Nutr. Metab., 73, pp. 17, 10.1159/000490843
  • Barreto, (2021), Rev. Lat. Am. Enfermagem, 29, pp. e3446, 10.1590/1518.8345.4466.3446
  • Shao, (2019), Nature, 574, pp. 117, 10.1038/s41586-019-1560-1
  • Shen, (2016), Nat. Med., 22, pp. 250, 10.1038/nm.4039
  • Francavilla, (2018), Ann. Nutr. Metab., 73, pp. 33, 10.1159/000490847
  • Lista, (2017), Pediatr. Med. Chir., 39, pp. 124
  • Luczynski, (2017), Nutr. Rev., 75, pp. 225, 10.1093/nutrit/nuw069
  • Martín-Peláez, S., Cano-Ibáñez, N., Pinto-Gallardo, M., and Amezcua-Prieto, C. (2022). The Impact of Probiotics, Prebiotics, and Synbiotics during Pregnancy or Lactation on the Intestinal Microbiota of Children Born by Cesarean Section: A Systematic Review. Nutrients, 14.
  • Bellanger, (2021), Front. Microbiol., 12, pp. 676622, 10.3389/fmicb.2021.676622
  • Gray, (2017), Front. Immunol., 8, pp. 365, 10.3389/fimmu.2017.00365
  • Porbahaie, (2020), Front. Immunol., 11, pp. 2141, 10.3389/fimmu.2020.02141
  • Trambusti, (2020), Front. Pediatr., 8, pp. 480, 10.3389/fped.2020.00480
  • Forsberg, (2016), Clin. Exp. Allergy, 46, pp. 1506, 10.1111/cea.12838
  • Gern, (2015), J. Allergy Clin. Immunol., 136, pp. 23, 10.1016/j.jaci.2015.05.017
  • Peroni, (2020), Front. Pediatr., 8, pp. 545, 10.3389/fped.2020.00545
  • Goh, (2021), Front. Immunol., 12, pp. 608372, 10.3389/fimmu.2021.608372
  • Trikamjee, (2021), Front. Pediatr., 8, pp. 577413, 10.3389/fped.2020.577413
  • Kantor, (2017), Expert Rev. Clin. Immunol., 13, pp. 15, 10.1080/1744666X.2016.1212660
  • Dang, (2013), J. Int. Med. Res., 41, pp. 1426, 10.1177/0300060513493692
  • Rusu, (2019), Exp. Ther. Med., 18, pp. 926
  • Garcia-Larsen, V., Ierodiakonou, D., Jarrold, K., Cunha, S., Chivinge, J., Robinson, Z., Geoghegan, N., Ruparelia, A., Devani, P., and Trivella, M. (2018). Diet during pregnancy and infancy and risk of allergic or autoimmune disease: A systematic review and meta-analysis. PLoS Med., 15.
  • Grot, M., Krupa-Kotara, K., Wypych-ślusarska, A., Grajek, M., and Białek-Dratwa, A. (2022). The Concept of Intrauterine Programming and the Development of the Neonatal Microbiome in the Prevention of SARS-CoV-2 Infection. Nutrients, 14.