Infiltración de la cámara anterior ocular en una paciente con leucemia no linfoblástica aguda
- C. Garrido Colino
- M.E. Mateos González
- M.J. Torres Valdivieso
- J. López Pérez
- C. Melero Moreno
- J.L. Vivanco Martínez
Argitalpen urtea: 2001
Alea: 55
Zenbakia: 1
Orrialdeak: 69-72
Mota: Artikulua
Laburpena
Unlike myeloid sarcoma, ocular involvement is unusual in acute non-lymphoblastic leukemia. A 9-month-old female infant with acute non-lympho-blastic leukemia M5 and evidence of active central nervous system (CNS) disease showed infiltration of the anterior chamber during therapy. At that time, the CNS disease was in completed remission. She was treated with topical corticosteroids, chemotherapy and bilateral ocular radiotherapy (total dose 1,000 cGy). The ocular manifestations responded well to treatment but hematologic response was poor. The patient died a few months later. Any ophthalmic manifestation in children with leukemia should be detected and treated early. Radiotherapy is warranted in infiltration of the anterior chamber of the eye. The presence of ocular, central CNS or bone marrow involvement indicates poor prognosis in acute childhood leukemia.