Prevención del déficit de memoria inducido por la exposición intensiva a etanol en ratón mediante el compuesto neuroprotector 3,3’-diindolilmetano

Resumo

Alcohol is the most widely consumed drug of abuse worldwide, with an estimated 5 % of all deaths globally being directly or indirectly linked to the use of this addictive substance, generating a high socioeconomic cost and posing a major threat to public health systems. Consumption profiles differ according to various aspects, such as social culture, economic status, sex and age. Binge drinking, which is defined as an abusive and excessive alcohol consumption in a short period of time, is most commonly practiced by adolescents and young adults, ages that are highly susceptible to the harmful effects of alcohol consumption. Of particular concern is the fact that the consequences induced by alcohol consumption in these early stages of life can be perpetuated into adulthood and old age...