Análisis comparativo entre la nefrectomía parcial y radical laparoscópica en pacientes con cáncer renal cT1

  1. LUIS CARDO, ADRIÁN
Supervised by:
  1. Carlos Hernández Fernández Director
  2. Felipe Herranz Amo Director

Defence university: Universidad Complutense de Madrid

Fecha de defensa: 17 January 2023

Committee:
  1. Jesús Moreno Sierra Chair
  2. E. Lledó García Secretary
  3. Ignacio Gómez García Committee member
  4. Guillermo Barbas Bernardos Committee member
  5. Carmen González Enguita Committee member

Type: Thesis

Teseo: 811041 DIALNET lock_openDocta Complutense editor

Abstract

Since the beginning of laparoscopic surgery for renal cell carcinoma (RCC) in the late 20th century, this approach has become commonly used as treatment of localized RCC. Historically, the main surgical technique was radical nephrectomy (RN), reserving partial nephrectomy (PN) for patients with single kidney, chronic kidney disease (CKD) or hereditary RCC. Currently, PN is recommended in patients with cT1 renal tumors when it is technically possible, even in patients with a healthy contralateral kidney and normal preoperative renal function. This recommendation is based on retrospective studies, where the oncological outcomes between PN and NR where similar, but with a greater detriment of renal function in patients treated with RN. However, recent retrospective series and one only existing clinical trial, have found no difference in overall survival (OS),despite the greater renal function detriment in NR-treated patients...