Antiagregantes plaquetarios y cirugía oralretirar o no retirar, esa es la cuestión

  1. Francisco González Fernández-Tresguerres 1
  2. Rebeca Serrano Zamora
  3. Laura Baca González
  4. Óscar Iglesias Velázquez 1
  5. Baoluo Xing Gao
  6. Isabel Ferández-Tresguerres Hernández-Gil 1
  1. 1 Universidad Complutense de Madrid. Facultad de Odontología
Zeitschrift:
Científica dental: Revista científica de formación continuada

ISSN: 1697-6398 1697-641X

Datum der Publikation: 2023

Ausgabe: 20

Nummer: 2

Seiten: 15-26

Art: Artikel

Andere Publikationen in: Científica dental: Revista científica de formación continuada

Zusammenfassung

Cardiovascular disease is one of the most prevalent systemic pathologies worldwide; those patients usually have had an acute coronary event which is treated with antiplatelet therapy. These drugs represent a challenge for the dentist, who must face a major dilemma: either maintain the drug, with the consequent bleeding risk, or withdraw it, with the possibility of thromboembolic complications, entailing a risk to the patient’s life. Therefore, dentists should know how to manage patients treated with these drugs when performing a surgical procedure or even a simple tooth extraction. The objectives of this narrative review are, firstly, to recall platelet physiology and the mechanisms of platelet thrombus formation; secondly, to go more deeply into the mechanisms of action of the different antiplatelet drugs; and thirdly, since there are no clinical guidelines on this topic, to critically review the existing guidelines related to the dental management, in order to prevent the appearance of possible complications, not only local, but more importantly, systemic complications. In these cases, before interrupting antiplatelet therapy, the risk of bleeding should be evaluated against the risk of generating a new thromboembolic episode, such as stent thrombosis or recurrence of the acute coronary accident, events that could put the patient’s life at risk.