Impact of a simplified treatment protocol for moderate acute malnutrition with a decentralized treatment approach in emergency settings of Niger

  1. Sánchez-Martínez, Luis Javier 2
  2. Charle-Cuéllar, Pilar 1
  3. Gado, Abdoul Aziz 6
  4. Dougnon, Abdias Ogobara 3
  5. Sanoussi, Atté 4
  6. Ousmane, Nassirou 4
  7. Lazoumar, Ramatoulaye Hamidou 7
  8. Toure, Fanta 3
  9. Vargas, Antonio 1
  10. Hernández, Candela Lucía 2
  11. López-Ejeda, Noemí 5
  1. 1 Action Against Hunger, Madrid, Spain
  2. 2 Unit of Physical Anthropology, Department of Biodiversity, Ecology and Evolution, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain
  3. 3 Action Against Hunger, West and Central Africa Regional Office, Dakar, Senegal
  4. 4 Nutrition Direction, Ministry of Health, Niamey, Niger
  5. 5 Unit of Physical Anthropology, Department of Biodiversity, Ecology and Evolution, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain, EPINUT Research Group (Ref. 920325), Faculty of Medicine, Complutense University of Madrid, Madrid, Spain
  6. 6 Action Against Hunger, Niamey, Niger
  7. 7 Centre de Recherche Médicale et Sanitaire (CERMES), Niamey, Niger
Revista:
Frontiers in Nutrition

ISSN: 2296-861X

Año de publicación: 2023

Volumen: 10

Tipo: Artículo

DOI: 10.3389/FNUT.2023.1253545 GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Frontiers in Nutrition

Resumen

Introduction: Of the 45.4 million children under five affected by acute malnutrition in the world, the majority (31.8 million) are affected by moderate acute malnutrition (MAM). Its treatment is particularly complex in emergency settings such as the Diffa region in Niger. This study aims to evaluate the effectiveness and coverage of a simplified treatment protocol with Community Health Workers (CHWs) as treatment providers.Methods: This study is a non-randomized controlled trial. The control group (n = 181) received the standard protocol currently used in country, delivered by nursing staff only in health centres and health posts, while the intervention group (n = 483) received the simplified protocol which included nursing at health centres and CHWs at health post as treatment providers.Results: The recovery rate was higher in the simplified protocol group (99.6% vs. 79.56%, p < 0.001) recording lower time to recover and higher anthropometric gain. Treatment coverage in the intervention group increased from 28.8% to 84.9% and reduced in the control group (25.3% to 13.6%). No differences were found in the recovery rate of children treated by CHWs and nursing staff.Conclusion: The outcomes using the simplified protocol exceeded humanitarian requirements and demonstrated improvements compared to the standard protocol showing that the simplified protocol could be safely provided by CHWs in an emergency context. Further research in other contexts is needed to scale up this intervention.

Referencias bibliográficas

  • (2021)
  • (2021)
  • de Onis, (2019), Public Health Nutr, 22, pp. 175, 10.1017/S1368980018002434
  • (2022)
  • (2018)
  • (2018)
  • Black, (2008), Lancet, 371, pp. 243, 10.1016/S0140-6736(07)61690-0
  • Black, (2013), Lancet, 382, pp. 427, 10.1016/S0140-6736(13)60937-X
  • Olofin, (2013), PLoS One, 8, pp. e64636, 10.1371/journal.pone.0064636
  • Stobaugh, (2017), Am J Clin Nutr, 106, pp. 657, 10.3945/ajcn.116.149799
  • (2012)
  • (2013)
  • Dalglish, (2020), Matern Child Nutr, 16, pp. e12920, 10.1111/mcn.12920
  • Bhutta, (2008), Lancet, 371, pp. 417, 10.1016/S0140-6736(07)61693-6
  • Lenters, (2013), BMC Public Health, 13, pp. S23, 10.1186/1471-2458-13-S3-S23
  • (2017)
  • Lelijveld, (2020), Matern Child Nutr, 16, pp. e12898, 10.1111/mcn.12898
  • Das, (2020), Nutrients, 12, pp. 116, 10.3390/nu12010116
  • Gluning, (2021), Trans R Soc Trop Med Hyg, 115, pp. 1317, 10.1093/trstmh/trab137
  • Lelijveld, (2021), Am J Clin Nutr, 114, pp. 955, 10.1093/ajcn/nqab137
  • Rogers, (2015), PLoS One, 10, pp. e0128666, 10.1371/journal.pone.0128666
  • James, (2016), PLoS One, 11, pp. e0153530, 10.1371/journal.pone.0153530
  • (2020)
  • Alé, (2016), Arch Public Health, 74, pp. 38, 10.1186/s13690-016-0149-5
  • Bliss, (2018), Glob Health Sci Pract, 6, pp. 552, 10.9745/GHSP-D-18-00105
  • López-Ejeda, (2020), PLoS One, 15, pp. e0227939, 10.1371/journal.pone.0227939
  • Dougnon, (2021), Nutrients, 13, pp. 4067, 10.3390/un13114067
  • Charle-Cuéllar, (2021), Children, 8, pp. 1132, 10.3390/children8121132
  • Charle-Cuéllar, (2021), Nutrients, 13, pp. 367, 10.3390/nu13020367
  • Bailey, (2020), PLoS Med, 17, pp. e1003192, 10.1371/journal.pmed.1003192
  • Daures, (2020), Br J Nutr, 123, pp. 756, 10.1017/S0007114519003258
  • Lelijveld, (2021), PLoS One, 16, pp. e0245477, 10.1371/journal.pone.0245477
  • Cazes, (2022), Lancet Glob Health, 10, pp. e510, 10.1016/S2214-109X(22)00041-9
  • Maust, (2015), J Nutr, 145, pp. 2604, 10.3945/jn.115.214957
  • (2006)
  • (2018)
  • (2008)
  • Myatt, (2012)
  • (2022), R: A language and environment for statistical computing
  • Rosner, (2011), Fundamentals of biostatistics, pp. 381
  • Kangas, (2022), Nutrients, 14, pp. 4923, 10.3390/nu14224923
  • Bradburn, (2003), Br J Cancer, 89, pp. 431, 10.1038/sj.bjc.6601119
  • Tsegaye, (2022), BMC Pediatr, 22, pp. 712, 10.1186/s12887-022-03767-4
  • (2018)
  • Álvarez-Morán, (2018), BMC Health Serv Res, 18, pp. 207, 10.1186/s12913-018-2987-z
  • López-Ejeda, (2018), Matern Child Nutr, 15, pp. e12719, 10.1111/mcn.12719
  • Wilunda, (2021), Sci Rep, 11, pp. 2342, 10.1038/s41598-021-81811-6
  • Oliphant, (2021), BMJ Glob Health, 6, pp. e005238, 10.1136/bmjgh-2021-005238
  • Cichon, (2023), Nutrients, 15, pp. 1076, 10.3390/nu15051076
  • Stobaugh, (2019), Mat Child Nutr, 15, pp. e12702, 10.1111/mcn.12702
  • Gebremichael, (2015), BMC Public Health, 15, pp. 1267, 10.1186/s12889-015-2593-5
  • Rashid, (2022), Front Public Health, 10, pp. 914837, 10.3389/fpubh.2022.914837
  • Cichon, (2023), Niger Nutrients, 15, pp. 3833, 10.3390/nu15173833
  • Yip, (1994), J Nutr, 124, pp. 2043S, 10.1093/jn/124.suppl_10.2043S