Aproximaciones a la epidemiología de la neuropatía óptica hereditaria de Leber en la comunidad autónoma de Madrid a través de una encuesta a los neuroftalmólogos

  1. Julio González-Martín-Moro 345
  2. José Alberto Reche-Sainz 6
  3. Teresa Gracia 6
  4. Borja Maroto Rodríguez 7
  5. Laura Cabrejas-Martínez 8
  6. Consuelo Gutiérrez-Ortíz 9
  7. Pilar L. Rojas 10
  8. Jesús Fraile-Maya 11
  9. N. Blanco Calvo 1
  10. Francisco José Muñoz-Negrete 2
  1. 1 Hospital Infantil Universitario Niño Jesus de Madrid
    info

    Hospital Infantil Universitario Niño Jesus de Madrid

    Madrid, España

    ROR https://ror.org/028brk668

  2. 2 Hospital Ramón y Cajal
    info

    Hospital Ramón y Cajal

    Madrid, España

    ROR https://ror.org/050eq1942

  3. 3 Hospital Universitario del Henares
    info

    Hospital Universitario del Henares

    Coslada, España

  4. 4 Fundación para la Investigación Biomédica del Hospital Infanta Sofía y del Hospital Universitario del Henares, San Sebastián de los Reyes, Madrid, España
  5. 5 Universidad Francisco de Vitoria
    info

    Universidad Francisco de Vitoria

    Pozuelo de Alarcón, España

    ROR https://ror.org/03ha64j07

  6. 6 Hospital Universitario 12 de Octubre
    info

    Hospital Universitario 12 de Octubre

    Madrid, España

    ROR https://ror.org/00qyh5r35

  7. 7 Hospital de Fuenlabrada
    info

    Hospital de Fuenlabrada

    Fuenlabrada, España

    ROR https://ror.org/04scbtr44

  8. 8 Fundación Jiménez Díaz
    info

    Fundación Jiménez Díaz

    Madrid, España

    ROR https://ror.org/049nvyb15

  9. 9 Hospital Universitario Príncipe de Asturias
    info

    Hospital Universitario Príncipe de Asturias

    Alcalá de Henares, España

    ROR https://ror.org/01az6dv73

  10. 10 Hospital General Universitario Gregorio Marañón
    info

    Hospital General Universitario Gregorio Marañón

    Madrid, España

    ROR https://ror.org/0111es613

  11. 11 Hospital Universitario La Paz
    info

    Hospital Universitario La Paz

    Madrid, España

    ROR https://ror.org/01s1q0w69

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Journal:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Year of publication: 2023

Volume: 98

Issue: 12

Pages: 673-679

Type: Article

DOI: 10.1016/J.OFTAL.2023.09.003 DIALNET GOOGLE SCHOLAR

More publications in: Archivos de la Sociedad Española de Oftalmologia

Abstract

Objective To estimate the epidemiology of Leber's optic neuropathy (NOHL) in the Region of Madrid. Material and methods The neuro-ophthalmologists who work at public hospitals of the CAM were interviewed by telephone. They were asked about the number of patients with NOHL that they had diagnosed during the time that they had been responsible for the neuro-ophthalmology department of that public hospital. The time worked and the population attended by the hospital were used to calculate the number of patient-years in follow-up by each center during the corresponding period. The basic information of each case (date of birth, mutation, and date of visual loss) was registered to avoid duplications. Results Our work estimates a global incidence of 2.34 cases for 10,000,000 inhabitants-year and a prevalence estimated from incidence of one case for each 106,682 inhabitants. This prevalence was very similar in all the studied areas and considerably lower than that reported by other studies. Conclusion This work constitutes the first approach to the epidemiology of this disease in Spain. The prevalence of NOHL in the region of Madrid is probably lower than that reported in the literature in other regions. The prevalence and the incidence were homogeneously low in the 26 studied areas.

Data source: Dialnet