Low-Frequency Contact Ultrasonic Debridement in Diabetic Foot Ulcer

Referencias bibliográficas

• van Netten JJ, Bus SA, Apelqvist J, Chen P, Chuter V, Fitridge R, et al. Definitions and criteria for diabetes-related foot disease (IWGDF 05 2023 update). Diabetes/Metabolism Research and Reviews. 2023;:1-6. DOI: 10.1002/dmrr.3654
• American Diabetes Association. 12. Retinopathy, neuropathy, and foot care: Standards of Care in Diabetes—2023. Diabetes Care. 2023;:S203-S215. DOI: 10.2337/dc23-S012
• Petersen BJ, Linde-Zwirble WT, Tan TW, Rothenberg GM, Salgado SJ, Bloom JD, et al. Higher rates of all-cause mortality and resource utilization during episodes-of-care for diabetic foot ulceration. Diabetes Research and Clinical Practice. 2022;:109182. DOI: 10.1016/j.diabres.2021.109182
• Zhang P, Lu J, Jing Y, Tang S, Zhu D, Bi Y. Global epidemiology of diabetic foot ulceration: A systematic review and meta-analysis. Annals of Medicine. 2017;:106-116. DOI: 10.1080/07853890.2016.1231932
• Armstrong DG, Boulton AJM, Bus SA. Diabetic foot ulcers and their recurrence. The New England Journal of Medicine. 2017;:2367-2375. DOI: 10.1056/NEJMra1615439
• Skrepnek GH, Mills JL, Lavery LA, Armstrong DG. Health care service and outcomes among an estimated 6.7 million ambulatory care diabetic foot cases in the U.S. Diabetes Care. 2017;:936-942. DOI: 10.2337/dc16-2189
• Armstrong DG, Wrobel J, Robbins JM. Guest editorial: Are diabetes-related wounds and amputations worse than cancer? International Wound Journal. 2007;:286-287. DOI: 10.1111/j.1742-481X.2007.00392.x
• Armstrong DG, Tan T, Boulton A, Bus S. Diabetic foot ulcers: A review. JAMA. 2023;:62-75. DOI: 10.1001/jama.2023.10578
• Sorber R, Abularrage CJ. Diabetic foot ulcers: Epidemiology and the role of multidisciplinary care teams. Seminars in Vascular Surgery. 2021;:47-53. DOI: 10.1053/j.semvascsurg.2021.02.006
• Schaper NC, van Netten JJ, Apelqvist J, Bus SA, Hinchliffe RJ, Lipsky BA, et al. Practical guidelines on the prevention and management of diabetic foot disease (IWGDF 2019 update). Diabetes/Metabolism Research and Reviews. 2020;:e3266
• Schultz GS, Sibbald RG, Falanga V, Ayello EA, Dowsett C, Harding K, et al. Wound bed preparation: A systematic approach to wound management. Wound Repair and Regeneration. 2003;:S1-S28. DOI: 10.1080/09608780500293018
• Harries RL, Bosanquet DC, Harding KG. Wound bed preparation: TIME for an update. International Wound Journal. 2016;:8-14. DOI: 10.1111/iwj.12662
• Steed DL, Attinger C, Brem H, Colaizzi T, Crossland M, Franz M, et al. Guidelines for the prevention of diabetic ulcers. Wound Repair and Regeneration. 2008;:169-174. DOI: 10.1111/j.1524-475X.2008.00357.x
• Chen L, Zhang S, Da J, Wu W, Ma F, Tang C, et al. A systematic review and meta-analysis of efficacy and safety of negative pressure wound therapy in the treatment of diabetic foot ulcer. Annals of Palliative Medicine. 2021;:10830-10839. DOI: 10.21037/apm-21-2476
• Zhang Z, Zhang W, Xu Y, Liu D. Efficacy of hyperbaric oxygen therapy for diabetic foot ulcers: An updated systematic review and meta-analysis. Asian Journal of Surgery. 2022;:68-78. DOI: 10.1016/j.asjsur.2021.07.047
• Gao W, Chen D, Liu G, Ran X. Autologous stem cell therapy for peripheral arterial disease: A systematic review and meta-analysis of randomized controlled trials. Stem Cell Research & Therapy. 2019;:1-14. DOI: 10.1186/s13287-019-1254-5
• Ennis WJ, Formann P, Mozen N, Massey J, Conner-Kerr T, Meneses P, et al. Ultrasound therapy for recalcitrant diabetic foot ulcers: Results of a randomized, double-blind, controlled, multicenter study. Ostomy Wound Management. 2005;:12
• Rayman G, Vas P, Dhatariya K, Driver V, Hartemann A, Londahl M, et al. Guidelines on use of interventions to enhance healing of chronic foot ulcers in diabetes (IWGDF 2019 update). Diabetes/Metabolism Research and Reviews. 2020;:e3283. DOI: 10.1002/dmrr.3283
• Dayya D, O’Neill OJ, Huedo-Medina TB, Habib N, Moore J, Iyer K. Debridement of diabetic foot ulcers. Advances in Wound Care. 2022;:666-686. DOI: 10.1089/wound.2021.0016
• Lázaro-Martínez JL, Álvaro-Afonso FJ, Ahluwaila R, Baker N, Ríos-Ruh J, Rivera-San Martin G, et al. Debridement and the Diabetic Foot. Beligium: D-Foot International; 2019
• Edwards J. Debridement of diabetic foot ulcers. Cochrane Database of Systematic Reviews. 2002;:CD003556. DOI: 10.1002/14651858.CD003556
• Strohal R, Apelqvist J, Dissemond J, O’Brien J, Piaggesi A, Rimdeika R, et al. EWMA document: Debridement. Journal of Wound Care. 2013;:S1-S52. DOI: 10.12968/jowc.2013.22.Sup1.S1
• Edwards J, Stapley S. Debridement of diabetic foot ulcers. Cochrane Database of Systematic Reviews. 2010;:CD003556. DOI: 10.1002/14651858.CD003556.pub2
• Nube VL, Alison JA, Twigg SM. Frequency of sharp wound debridement in the management of diabetes-related foot ulcers: Exploring current practice. Journal of Foot and Ankle Research. 2021;:1-7. DOI: 10.1186/s13047-021-00489-1
• Everett E, Mathioudakis N. Update on management of diabetic foot ulcers. Annals of the New York Academy of Sciences. 2018;:153-165. DOI: 10.1111/nyas.13569
• Scepankova H, Combarros- Fuertes P, Fresno JM, Tornadijo ME, Dias MS, Pinto CA, et al. Role of honey in advanced wound care. Molecules. 2021;:1-19. DOI: 10.3390/molecules26164784
• Moya-López J, Costela- Ruiz V, Garciá-Recio E, Sherman RA, De Luna-Bertos E. Advantages of maggot debridement therapy for chronic wounds: A bibliographic review. Advances in Skin & Wound Care. 2020;:515-525. DOI: 10.1097/01.ASW.0000695776.26946.68
• Nishijima A, Gosho M, Yoshida R, Yanagibayashi S, Takikawa M, Nishijima J, et al. Effective wound bed preparation using maggot debridement therapy for patients with critical limb ischaemia. Journal of Wound Care. 2017;:483-489. DOI: 10.12968/jowc.2017.26.8.483
• Nube VL, White JM, Brewer K, Veldhoen D, Meler C, Frank G, et al. A randomized trial comparing weekly with every second week sharp debridement in people with diabetes-related foot ulcers shows similar healing outcomes: Potential benefit to resource utilization. Diabetes Care. 2021;:e203-e205. DOI: 10.2337/dc21-1454
• Elraiyah T, Domecq JP, Prutsky G, Tsapas A, Nabhan M, Frykberg RG, et al. A systematic review and meta-analysis of débridement methods for chronic diabetic foot ulcers. Journal of Vascular Surgery. 2016;:37S-45S. DOI: 10.1016/j.jvs.2015.10.002
• Hingorani A, Lamuraglia GM, Henke P, Meissner MH, Loretz L, Zinszer KM, et al. The management of diabetic foot: A clinical practice guideline by the Society for Vascular Surgery in collaboration with the American Podiatric Medical Association and the Society for Vascular Medicine. Journal of Vascular Surgery. 2016;:3S-21S. DOI: 10.1016/j.jvs.2015.10.003
• Hinchliffe RJ, Forsythe RO, Apelqvist J, Boyko EJ, Fitridge R, Hong JP, et al. Guidelines on diagnosis, prognosis and management of peripheral artery disease in patients with a foot ulcer and diabetes (IWGDF 2019 update). Diabetes/Metabolism Research and Reviews. 2020;:e3276
• Murphy CA, Houghton P, Brandys T, Rose G, Bryant D. The effect of 22.5 kHz low-frequency contact ultrasound debridement (LFCUD) on lower extremity wound healing for a vascular surgery population: A randomised controlled trial. International Wound Journal. 2018;:460-472. DOI: 10.1111/iwj.12887
• Kotronis G, Vas PRJ. Ultrasound devices to treat chronic wounds: The current level of evidence. The International Journal of Lower Extremity Wounds. 2020;:341-349. DOI: 10.1177/1534734620946660
• Stanisic MM, Provo BJ, Larson DL, Kloth LC. Wound debridement with 25 kHz ultrasound. Advances in Skin & Wound Care. 2005;:484-490. DOI: 10.1097/00129334-200511000-00012
• Butcher G, Pinnuck L. Wound bed preparation: Ultrasonic-assisted debridement. The British Journal of Nursing. 2013;:S37-S43. DOI: 10.12968/bjon.2013.22.Sup4.S36
• Herberger K, Franzke N, Blome C, Kirsten N, Augustin M. Efficacy, tolerability and patient benefit of ultrasound-assisted wound treatment versus surgical debridement: A randomized clinical study. Dermatology. 2011;:244-249. DOI: 10.1159/000326116
• Kavros SJ, Coronado R. Diagnostic and therapeutic ultrasound on venous and arterial ulcers: A focused review. Advances in Skin & Wound Care. 2018;:55-65. DOI: 10.1097/01.ASW.0000527967.10613.87
• Chang Y-JR, Perry J, Cross K. Low-frequency ultrasound debridement in chronic wound healing: A systematic review of current evidence. Plastic Surgery. 2017;:21-26. DOI: 10.1177/2292550317693813
• Rastogi A, Bhansali A, Ramachandran S. Efficacy and safety of low-frequency, noncontact airborne ultrasound therapy (Glybetac) for neuropathic diabetic foot ulcers: A randomized, double-blind, sham-control study. The International Journal of Lower Extremity Wounds. 2019;:81-88. DOI: 10.1177/1534734619832738
• Voigt J, Wendelken M, Driver V, Alvarez OM. Low-frequency ultrasound (20-40 kHz) as an adjunctive therapy for chronic wound healing: A systematic review of the literature and meta-analysis of eight randomized controlled trials. The International Journal of Lower Extremity Wounds. 2011;:190-199. DOI: 10.1177/1534734611424648
• Swanson T, Lázaro-Martínez JL, Braumann C, Kirchhoff J-B, Gaechter B, van Acker K. Ultrasonic-assisted wound debridement: Report from a closed panel meeting. Journal of Wound Care. 2020;:128-135
• Braumann C, Lázaro-Martínez JL, Schultz G, Swanson T. Söring UAW made easy. Wound International. 2017;:1-6
• Driver VR, Yao M, Miller CJ. Noncontact low-frequency ultrasound therapy in the treatment of chronic wounds: A meta-analysis. Wound Repair and Regeneration. 2011;:475-480. DOI: 10.1111/j.1524-475X.2011.00701.x
• Kataoka Y, Kunimitsu M, Nakagami G, Koudounas S, Weller CD, Sanada H. Effectiveness of ultrasonic debridement on reduction of bacteria and biofilm in patients with chronic wounds: A scoping review. International Wound Journal. 2021;:176-186. DOI: 10.1111/iwj.13509
• Kamineni S, Huang C. The antibacterial effect of sonication and its potential medical application. Journal of Sicot. 2019;:19. DOI: 10.1051/sicotj/2019017
• Madhok BM, Vowden K, Vowden P. New techniques for wound debridement. International Wound Journal. 2013;:247-251. DOI: 10.1111/iwj.12045
• Swanson T, Hirst C, Salzman S, Frescos N. The influence of technique and type of sonotrode on debridement and patient experience using a low frequency ultrasound contact debridement device; a case series. Wound Practice and Research. 2023;:19-27. DOI: 10.33235/wpr.31.1.19-27
• Söring. Ultrasonic Generator SONOCA 185 Instructions for Use 2015. Available from:
• Michailidis L, Kotsanas D, Orr E, Coombes G, Bergin S, Haines T, et al. Does the new low-frequency ultrasonic debridement technology pose an infection control risk for clinicians, patients, and the clinic environment? American Journal of Infection Control. 2016;:1656-1659. DOI: 10.1016/j.ajic.2016.04.228
• Yao M, Hasturk H, Kantarci A, Gu G, Garcia-Lavin S, Fabbi M, et al. A pilot study evaluating non-contact low-frequency ultrasound and underlying molecular mechanism on diabetic foot ulcers. International Wound Journal. 2014;:586-593. DOI: 10.1111/iwj.12005
• Lázaro-Martínez JL, Álvaro- Afonso FJ, García-Álvarez Y, Molines-Barroso RJ, García-Morales E, Sevillano-Fernández D. Ultrasound-assisted debridement of neuroischaemic diabetic foot ulcers, clinical and microbiological effects: A case series. Journal of Wound Care. 2018;:278-286. DOI: 10.12968/jowc.2018.27.5.278
• Lázaro-Martínez JL, Álvaro- Afonso FJ, Sevillano-Fernández D, García-Álvarez Y, Sanz-Corbalan I, García-Morales E. Cellular proliferation, dermal repair, and microbiological effectiveness of ultrasound-assisted wound debridement (UAW) versus standard wound treatment in complicated diabetic foot ulcers (DFU): An open-label randomized controlled trial. Journal of Clinical Medicine. 2020;:1-13. DOI: 10.3390/jcm9124032
• Flores-Escobar S, Álvaro-Afonso FJ, García-álvarez Y, López-Moral M, Lázaro-Martínez JL, García-Morales E. Ultrasound-assisted wound (UAW) debridement in the treatment of diabetic foot ulcer: A systematic review and meta-analysis. Journal of Clinical Medicine. 2022;:1911. DOI: 10.3390/jcm11071911
• Chen H, Xiao T, Zhang L, Liu N, Liang X, Li T, et al. Effect of ultrasound-supported wound debridement in subjects with diabetic foot ulcers: A meta-analysis. International Wound Journal. 2023;:2618-2625. DOI: 10.1111/iwj.14133
• Chen H, Yu Z, Liu N, Huang J, Liang X, Liang X, et al. The efficacy of low-frequency ultrasound as an added treatment for chronic wounds: A meta-analysis. International Wound Journal. 2023;:448-457. DOI: 10.1111/iwj.13893
• Chen P, Vilorio NC, Dhatariya K, Jeffcoate W, Lobmann R, McIntosh C, et al. Guidelines on interventions to enhance healing of foot ulcers in people with diabetes (IWGDF 2023 update). Diabetes/Metabolism Research and Reviews. 2023;:e3644. DOI: 10.1002/dmrr.3644