Glomerulopatía colapsante en un paciente con Covid-19. Reporte de caso

  1. Palacios-Guillén, Alaciel 1
  2. Hernández-Obando, Enrique 2
  3. Asato-Higa, Carmen 3
  4. Sánchez-Sánchez, César 4
  5. Mejía-Valencia, Aracely 4
  6. Sumire-Umeres, Julia 3
  1. 1 Hospital Nacional Daniel Alcides Carrión, Lima, Perú. Universidad Peruana Cayetano Heredia, Lima, Perú
  2. 2 Hospital Nacional Daniel Alcides Carrión, Lima, Perú
  3. 3 Laboratorios Integrados, Lima, Perú
  4. 4 Universidad Nacional Mayor de San Marcos, Lima, Perú
Journal:
Revista Médica Herediana

ISSN: 1729-214X 1018-130X

Year of publication: 2023

Issue Title: January - March

Volume: 34

Issue: 1

Pages: 27-31

Type: Article

DOI: 10.20453/RMH.V34I1.4449 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

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Abstract

Acute renal injury due to collapsing glomerulonephritis is associated with high morbidity and mortality, requiring chronic dialysis, COVID-19 is one of its causes. A 17-year-old male patient presented with a four-month history of edema, foamy urine and reduction in the urine flow; anasarca was observed at physical examination. Laboratory values showed creatinine 4,2 mg/dl; albumin 1,9 gr/dl; cholesterol and triglycerides were high; proteinuria 6,7 gr/24h: leucocyturia and hematuria with negative urine culture. Serologies for HIV, syphilis and hepatitis were negative. Studies for systemic lupus were negative. An antigenic test for SARS-CoV-2 was positive as well as an IgG. Renal Biopsy showed Focal and Segmental Glomerulosclerosis, Collapsing variant. He received corticosteroids and cyclosporine. Creatinine improved; proteinuria remained >3 gr/24 hours.