Synthesis of N,N′‐Disulfonylamidines from Sulfonamides and Alkynes by a Two‐Step, One‐Pot Reaction with Nonafluorobutanesulfonyl Azide

José Ramón Suárez; Joanna Kwiczak; Katarzyna Grenda; M. Luisa Jimeno; Jose Luis Chiara

doi:10.1002/ADSC.201201001

Synthesis of N,N′‐Disulfonylamidines from Sulfonamides and Alkynes by a Two‐Step, One‐Pot Reaction with Nonafluorobutanesulfonyl Azide

José Ramón Suárez ¹
Joanna Kwiczak ¹
Katarzyna Grenda ¹
M. Luisa Jimeno ²
Jose Luis Chiara ¹

1 Instituto de Química Orgánica General, IQOG-CSIC, Juan de la Cierva 3, E-28006 Madrid, Spain
2 Centro de Química Orgánica “Lora Tamayo”, CENQUIOR-CSIC, Juan de la Cierva 3, E-28006 Madrid, Spain

Aldizkaria:

Advanced Synthesis & Catalysis

ISSN: 1615-4150, 1615-4169

Argitalpen urtea: 2013

Alea: 355

Zenbakia: 5

Orrialdeak: 913-918

Mota: Artikulua

DOI: 10.1002/ADSC.201201001 GOOGLE SCHOLAR Sarbide irekia editor

Beste argitalpen batzuk: Advanced Synthesis & Catalysis

Laburpena

Nonafluorobutanesulfonyl azide is an advantageous alternative to triflyl azide for the efficient synthesis of sulfonyl azides from sulfonamides in terms of its higher reactivity, lower cost, and non-hazardous nature. The reagent has proven its utility in a novel synthesis of N,N′-disulfonylamidines from available sulfonamides by a copper-catalyzed two-step, one-pot sequential process with added terminal alkynes.

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