Acute stress induces long-term metabolic, functional and structural remodeling of the heart

  1. Yoganathan, Thulaciga
  2. Perez-Liva, Mailyn
  3. Balvay, Daniel 1
  4. Le Gall, Morgane 23
  5. Lallemand, Alice
  6. Certain, Anaïs 3
  7. Autret, Gwennhael
  8. Mokrani, Yasmine
  9. Guillonneau, François
  10. Bruce, Johanna 3
  11. Nguyen, Vincent T.
  12. Gencer, Umit
  13. Schmitt, Alain
  14. Lager, Franck
  15. Guilbert, Thomas
  16. Bruneval, Patrick
  17. Vilar, José
  18. Maissa, Nawal
  19. Mousseaux, Elie
  20. Viel, Thomas
  21. Renault, Gilles
  22. Kachenoura, Nadjia 4
  23. Tavitian, Bertrand 1
  1. 1 French Institute of Health and Medical Research
    info

    French Institute of Health and Medical Research

    París, Francia

    ROR https://ror.org/02vjkv261

  2. 2 Institut Cochin
    info

    Institut Cochin

    París, Francia

    ROR https://ror.org/051sk4035

  3. 3 Université Paris-Cité
  4. 4 Institute of Cardiometabolism and Nutrition
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Editorial: figshare

Año de publicación: 2023

Tipo: Dataset

DOI: 10.6084/M9.FIGSHARE.23283086 GOOGLE SCHOLAR lock_openAcceso abierto editor

Resumen

Takotsubo syndrome, a stress-induced cardiomyopathy mimicking an acute coronary syndrome but formerly considered a benign reversible disease, increases the risk of heart failure and cardiac death. Here, the authors show that the function and structure of the heart engage in a continuous deterioration after acute stress and link this snowball effect to deviated control of cardiac metabolism.