Replication Data for: Spatial metabolomics identifies LPC(18:0) and LPA(18:1) in advanced atheroma with translation to plasma for cardiovascular risk estimation

  1. Balluff, B. 1
  2. Alvarez-Llamas, G. 2
  1. 1 (Maastricht University)
  2. 2 (IIS-Fundación Jiménez Díaz Hospital, Madrid)

Editor: DataverseNL

Año de publicación: 2023

Tipo: Dataset

DOI: 10.34894/TKBBK4 lock_openAcceso abierto editor

Resumen

* MALDI mass spectrometry imaging data (FT-ICR, 40 µm lateral resolution) of 9 human and 22 animal model (LDLR-deficient) atherosclerotic tissue samples. * LC-MS data of LPC(18:0) and LPA(18:1) in human plasma from subjects with elective coronary artery bypass grafting (CABG, CV-risk group, n=27) and a control group (n=27). * High-spatial resolution MALDI mass spectrometry imaging data (TOF, 10 µm lateral resolution) of 1 animal model (LDLR-deficient) atherosclerotic tissue sample. * High-resolution MALDI-2 mass spectrometry imaging data (TOF, 10 µm lateral resolution) of 1 animal model (LDLR-deficient) atherosclerotic tissue sample for imaging cholesterol and derivative molecules. * MS/MS data of LPC(18:0) and LPA(18:1) from tissue