Lymphoid Seeding in the Thymus: A New Function for Ephb2 and Ephb3

  1. David Alfaro 1
  2. Javier García-Ceca 1
  3. Sara Montero Herradón 1
  4. Agustín G. Zapata 1
  1. 1 Department of Cell Biology, Faculty of Biology, Complutense University of Madrid, Madrid, Spain
Revista:
Immunogenetics: Open Access

ISSN: 2796-0870

Año de publicación: 2016

Volumen: 1

Número: 3

Tipo: Artículo

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Resumen

We have found that the lack of EphB2 or EphB3 courses with decreased proportions of early thymic progenitors seeding the adult thymuses of EphB-deficient mice. The origin of these deficiencies is commented on the basis ofprofound alterations observed in the thymic epithelium of these mutant mice.

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