Estrategias para la mejora de la persistencia y la eficacia de las células CAR NK para el tratamiento del mieloma múltiple refractario y en recaída

  1. ENCINAS MAYORAL, JESSICA
Supervised by:
  1. Joaquín Martínez López Director
  2. Antonio Valeri Lozano Director
  3. Daniel Primo Ramos Director

Defence university: Universidad Complutense de Madrid

Fecha de defensa: 08 March 2024

Committee:
  1. Amalia Diez Martín Chair
  2. Maria Teresa Cedena Romero Secretary
  3. Julio García Suárez Committee member
  4. María Ángela Aznar Gómez Committee member
  5. Paula Río Galdo Committee member

Type: Thesis

Teseo: 842731 DIALNET lock_openDocta Complutense editor

Abstract

Multiple myeloma (MM) is a neoplasm characterized by the clonal proliferation of pathologic plasma cells (PC), mainly in the bone marrow (BM). It constitutes 10% of hematologic tumors and 1,8% of all neoplasms. Classic symptomatology is included in CRAB acroyn, hypercalcemia, renal failure, anemia and bone lytic lesions...