Mecanismos de señalización celular en enfermedades hepáticas, cardiovasculares y cáncer
University of Pennsylvania
Filadelfia, Estados UnidosPublicaciones en colaboración con investigadores/as de University of Pennsylvania (15)
2024
2022
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Combined hepatocellular-cholangiocarcinoma derives from liver progenitor cells and depends on senescence and IL-6 trans-signaling
Journal of Hepatology, Vol. 77, Núm. 6, pp. 1631-1641
2021
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NAC blocks Cystatin C amyloid complex aggregation in a cell system and in skin of HCCAA patients
Nature Communications, Vol. 12, Núm. 1
2019
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ARAF recurrent mutation causes central conducting lymphatic anomaly treatable with a MEK inhibitor
Nature Medicine, Vol. 25, Núm. 7, pp. 1116-1122
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RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation
Leukemia, Vol. 33, Núm. 8, pp. 2006-2021
2018
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Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” (Redox Biol. (2017) 13 (94–162)(S2213231717303373)(10.1016/j.redox.2017.05.007))
Redox Biology
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Pathogenic variant in EPHB4 results in central conducting lymphatic anomaly
Human Molecular Genetics, Vol. 27, Núm. 18, pp. 3233-3245
2017
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European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
Redox Biology, Vol. 13, pp. 94-162
2016
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C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms
Oncotarget, Vol. 7, Núm. 29, pp. 45060-45078
2015
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PKCε is an essential mediator of prostate cancer bone metastasis
Molecular Cancer Research, Vol. 13, Núm. 9, pp. 1336-1346
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p38 MAPK down-regulates fibulin 3 expression through methylation of gene regulatory sequences: Role in migration and invasion
Journal of Biological Chemistry, Vol. 290, Núm. 7, pp. 4383-4397
2014
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Transcriptional regulation of oncogenic protein kinase Cε (PKCε) by STAT1 and Sp1 proteins
Journal of Biological Chemistry, Vol. 289, Núm. 28, pp. 19823-19838
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β3-Chimaerin, a novel member of the chimaerin Rac-GAP family
Molecular Biology Reports, Vol. 41, Núm. 4, pp. 2067-2076
2013
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Coordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol
Nature Communications, Vol. 4
2012
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Rac signaling in breast cancer: A tale of GEFs and GAPs
Cellular Signalling, Vol. 24, Núm. 2, pp. 353-362