Mecanismos de señalización celular en enfermedades hepáticas, cardiovasculares y cáncer
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Universidad de Salamanca
Salamanca, EspañaPublicaciones en colaboración con investigadores/as de Universidad de Salamanca (20)
2024
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Platelet C3G: a key player in vesicle exocytosis, spreading and clot retraction
Cellular and Molecular Life Sciences, Vol. 81, Núm. 1
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The hepatocyte epidermal growth factor receptor (EGFR) pathway regulates the cellular interactome within the liver fibrotic niche
Journal of Pathology, Vol. 263, Núm. 4-5, pp. 482-495
2022
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C3G down-regulation enhances pro-migratory and stemness properties of oval cells by promoting an epithelial-mesenchymal-like process
International journal of biological sciences, Vol. 18, Núm. 15, pp. 5873-5884
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New functions of C3G in platelet biology: Contribution to ischemia-induced angiogenesis, tumor metastasis and TPO clearance
Frontiers in Cell and Developmental Biology, Vol. 10
2021
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Anti-miR-518d-5p overcomes liver tumor cell death resistance through mitochondrial activity
Cell Death and Disease, Vol. 12, Núm. 6
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C3G downregulation induces the acquisition of a mesenchymal phenotype that enhances aggressiveness of glioblastoma cells
Cell Death and Disease, Vol. 12, Núm. 4
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C3G protein, a new player in glioblastoma
International Journal of Molecular Sciences, Vol. 22, Núm. 18
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Contribution of c3g and other gefs to liver cancer development and progression
Hepatoma Research, Vol. 7
2020
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C3G contributes to platelet activation and aggregation by regulating major signaling pathways
Signal Transduction and Targeted Therapy, Vol. 5, Núm. 1
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C3G is upregulated in hepatocarcinoma, contributing to tumor growth and progression and to HGF/MET pathway activation
Cancers, Vol. 12, Núm. 8, pp. 1-22
2018
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C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation
Cell Communication and Signaling, Vol. 16, Núm. 1
2017
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C3G promotes a selective release of angiogenic factors from activated mouse platelets to regulate angiogenesis and tumor metastasis
Oncotarget, Vol. 8, Núm. 67, pp. 110994-111011
2016
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C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms
Oncotarget, Vol. 7, Núm. 29, pp. 45060-45078
2013
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C3G forms complexes with Bcr-Abl and p38α MAPK at the focal adhesions in chronic myeloid leukemia cells: Implication in the regulation of leukemic cell adhesion
Cell Communication and Signaling, Vol. 11, Núm. 1
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Met signaling in cardiomyocytes is required for normal cardiac function in adult mice
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1832, Núm. 12, pp. 2204-2215
2012
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C3G transgenic mouse models with specific expression in platelets reveal a new role for C3G in platelet clotting through its GEF activity
Biochimica et Biophysica Acta - Molecular Cell Research, Vol. 1823, Núm. 8, pp. 1366-1377
2010
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C3G down-regulates p38 MAPK activity in response to stress by Rap-1 independent mechanisms: Involvement in cell death
Cellular Signalling, Vol. 22, Núm. 3, pp. 533-542
2009
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C3G silencing enhances STI-571-induced apoptosis in CML cells through p38 MAPK activation, but it antagonizes STI-571 inhibitory effect on survival
Cellular Signalling, Vol. 21, Núm. 7, pp. 1229-1235
2004
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IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes
Hepatology, Vol. 40, Núm. 6, pp. 1285-1294
2003
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Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes
Diabetes, Vol. 52, Núm. 9, pp. 2239-2248