Publicaciones en colaboración con investigadores/as de Centro Nacional de Investigaciones Oncológicas (8)

2023

  1. Cancer-Stem-Cell Phenotype-Guided Discovery of a Microbiota-Inspired Synthetic Compound Targeting NPM1 for Leukemia

    JACS Au

2020

  1. Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: a multi-omics analysis in ovarian cancer

    Scientific Reports, Vol. 10, Núm. 1

2019

  1. A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia

    Journal of Medicinal Chemistry, Vol. 62, Núm. 13, pp. 6035-6046

  2. Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells

    Nature Communications, Vol. 10, Núm. 1

2017

  1. Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells

    Oncotarget, Vol. 8, Núm. 7, pp. 11600-11613

2015

  1. Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells

    International Journal of Cancer, Vol. 136, Núm. 9, pp. 2078-2090

  2. Role of cannabinoid receptor CB<inf>2</inf> in HER2 pro-oncogenic signaling in breast cancer

    Journal of the National Cancer Institute, Vol. 107, Núm. 6

2012

  1. New synthetic inhibitors of fatty acid synthase with anticancer activity

    Journal of Medicinal Chemistry, Vol. 55, Núm. 11, pp. 5013-5023