RAFAEL
LEÓN MARTÍNEZ
Profesor asociado
Publicacións nas que colabora con RAFAEL LEÓN MARTÍNEZ (12)
2022
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Curcumin-piperlongumine hybrids with a multitarget profile elicit neuroprotection in in vitro models of oxidative stress and hyperphosphorylation
Antioxidants, Vol. 11, Núm. 1
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Enantioselective Synthesis and Pharmacological Evaluation of Aza‐CGP37157–Lipoic Acid Hybrids for the Treatment of Alzheimer’s Disease
Antioxidants, Vol. 11, Núm. 1
2021
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Bisavenathramide analogues as nrf2 inductors and neuroprotectors in in vitro models of oxidative stress and hyperphosphorylation
Antioxidants, Vol. 10, Núm. 6
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Enhanced stability and bioactivity of natural anticancer topoisomerase i inhibitors through cyclodextrin complexation
Pharmaceutics, Vol. 13, Núm. 10
2020
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Antioxidant, anti-inflammatory and neuroprotective profiles of novel 1,4-dihydropyridine derivatives for the treatment of alzheimer’s disease
Antioxidants, Vol. 9, Núm. 8, pp. 1-20
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Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties
Drug Development Research, Vol. 81, Núm. 3, pp. 283-294
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NRF2 Regulation Processes as a Source of Potential Drug Targets against Neurodegenerative Diseases
Biomolecules, Vol. 10, Núm. 6
2017
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Addition to "ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia"
ACS chemical neuroscience, Vol. 8, Núm. 1, pp. 210
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Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease
Scientific Reports, Vol. 7
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ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia
ACS Chemical Neuroscience, Vol. 8, Núm. 1, pp. 67-81
2014
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New 5-unsubstituted dihydropyridines with improved CaV1.3 selectivity as potential neuroprotective agents against ischemic injury
Journal of Medicinal Chemistry, Vol. 57, Núm. 10, pp. 4313-4323
2013
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Identification of 4,6-diaryl-1,4-dihydropyridines as a new class of neuroprotective agents
MedChemComm, Vol. 4, Núm. 3, pp. 590-594