Heterociclos de interés biológico y terapéutico
King Saud University
Riad, Arabia SaudíPublicacions en col·laboració amb investigadors/es de King Saud University (15)
2021
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Synthesis of Fused Quinoline Derivatives from Easily Accessible N-(2-aminobenzylidene)-4-methylanilines under Catalyst-Free Conditions in Water
ChemistrySelect, Vol. 6, Núm. 38, pp. 10436-10439
2019
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D-Ring-Modified Analogues of Luotonin A with Reduced Planarity: Design, Synthesis, and Evaluation of Their Topoisomerase Inhibition-Associated Cytotoxicity
BioMed Research International, Vol. 2019
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Design and synthesis of A- and D ring-modified analogues of luotonin A with reduced planarity
Tetrahedron Letters, Vol. 60, Núm. 23, pp. 1514-1517
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Multicomponent domino protocol for the stereoselective synthesis of novel pyrrolo[3,2-c]quinolinone hybrid heterocycles
Tetrahedron Letters, Vol. 60, Núm. 8, pp. 602-605
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Spirooxindole-pyrrolidine heterocyclic hybrids promotes apoptosis through activation of caspase-3
Bioorganic and Medicinal Chemistry, Vol. 27, Núm. 12, pp. 2487-2498
2018
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Highly functionalized pyrrolidine analogues: stereoselective synthesis and caspase-dependent apoptotic activity
RSC Advances, Vol. 8, Núm. 72, pp. 41226-41236
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Multicomponent domino synthesis, anticancer activity and molecular modeling simulation of complex dispirooxindolopyrrolidines
Molecules, Vol. 23, Núm. 5
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Regio and stereoselective synthesis of anticancer spirooxindolopyrrolidine embedded piperidone heterocyclic hybrids derived from one-pot cascade protocol
Chemistry Central Journal, Vol. 12, Núm. 1
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Regio- and diastereoselective synthesis of anticancer spirooxindoles derived from tryptophan and histidine via three-component 1,3-dipolar cycloadditions in an ionic liquid
Tetrahedron, Vol. 74, Núm. 38, pp. 5358-5366
2017
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Design, synthesis and antiproliferative activity of decarbonyl luotonin analogues
European Journal of Medicinal Chemistry, Vol. 138, pp. 932-941
2016
2015
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An expedient regio- and diastereoselective synthesis of hybrid frameworks with embedded spiro[9,10]dihydroanthracene [9,3']-pyrrolidine and Spiro[oxindole-3,2'-pyrrolidine] motifs via an ionic liquid-mediated multicomponent reaction
Molecules, Vol. 20, Núm. 9, pp. 16142-16153
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Dipolar Cycloaddition-Based Multicomponent Reactions in Ionic Liquids: A Green, Fully Stereoselective Synthesis of Novel Polycyclic Cage Systems with the Generation of Two New Azaheterocyclic Rings
Synthesis (Germany), Vol. 47, Núm. 18, pp. 2721-2730
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Straightforward synthesis of pyrrolo[3,4-b]quinolines through intramolecular Povarov reactions
Tetrahedron Letters, Vol. 56, Núm. 49, pp. 6900-6903
2012
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Domino reactions in water: Diastereoselective synthesis of densely functionalized indolyldihydrofuran derivatives
Green Chemistry, Vol. 14, Núm. 3, pp. 750-757