Heterociclos de interés biológico y terapéutico
Universidad Autónoma de Madrid
Madrid, EspañaPublications in collaboration with researchers from Universidad Autónoma de Madrid (16)
2022
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Curcumin-piperlongumine hybrids with a multitarget profile elicit neuroprotection in in vitro models of oxidative stress and hyperphosphorylation
Antioxidants, Vol. 11, Núm. 1
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Multitarget Hybrid Fasudil Derivatives as a New Approach to the Potential Treatment of Amyotrophic Lateral Sclerosis
Journal of Medicinal Chemistry, Vol. 65, Núm. 3, pp. 1867-1882
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Small Molecules as Toll-like Receptor 4 Modulators Drug and In-House Computational Repurposing
Biomedicines, Vol. 10, Núm. 9
2021
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Bisavenathramide analogues as nrf2 inductors and neuroprotectors in in vitro models of oxidative stress and hyperphosphorylation
Antioxidants, Vol. 10, Núm. 6
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Enhanced stability and bioactivity of natural anticancer topoisomerase i inhibitors through cyclodextrin complexation
Pharmaceutics, Vol. 13, Núm. 10
2020
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Antioxidant, anti-inflammatory and neuroprotective profiles of novel 1,4-dihydropyridine derivatives for the treatment of alzheimer’s disease
Antioxidants, Vol. 9, Núm. 8, pp. 1-20
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Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties
Drug Development Research, Vol. 81, Núm. 3, pp. 283-294
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NRF2 Regulation Processes as a Source of Potential Drug Targets against Neurodegenerative Diseases
Biomolecules, Vol. 10, Núm. 6
2017
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Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease
Scientific Reports, Vol. 7
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ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia
ACS Chemical Neuroscience, Vol. 8, Núm. 1, pp. 67-81
2014
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New 5-unsubstituted dihydropyridines with improved CaV1.3 selectivity as potential neuroprotective agents against ischemic injury
Journal of Medicinal Chemistry, Vol. 57, Núm. 10, pp. 4313-4323
2013
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Identification of 4,6-diaryl-1,4-dihydropyridines as a new class of neuroprotective agents
MedChemComm, Vol. 4, Núm. 3, pp. 590-594
2010
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Discovery of a class of diketopiperazines as antiprion compounds
ChemMedChem, Vol. 5, Núm. 8, pp. 1324-1334
1997
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Mineralogical and chemical modifications in soils affected by a forest fire in the Mediterranean area
Science of the Total Environment, Vol. 204, Núm. 1, pp. 89-96
1996
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Analytical applications of retinoid-cyclodextrin inclusion complexes 1. Characterization of a retinal-β-cyclodextrin complex
Journal of Pharmaceutical and Biomedical Analysis
1980
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Structure-activity relationships between cryptopleurine and related compounds acting on yeast cell-free systems
Current Microbiology: An International Journal, Vol. 4, Núm. 2, pp. 81-84