María Antonia
Blasco Marhuenda
Publicaciones en las que colabora con María Antonia Blasco Marhuenda (28)
2022
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A mouse model for Li-Fraumeni-Like Syndrome with cardiac angiosarcomas associated to POT1 mutations
PLoS Genetics, Vol. 18, Núm. 6
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Consequences of telomere dysfunction in fibroblasts, club and basal cells for lung fibrosis development
Nature Communications, Vol. 13, Núm. 1
2020
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The mTOR pathway is necessary for survival of mice with short telomeres
Nature Communications, Vol. 11, Núm. 1
2018
2010
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TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice
Developmental Cell, Vol. 18, Núm. 5, pp. 775-789
2009
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Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice
Genes and Development, Vol. 23, Núm. 17, pp. 2060-2075
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MSH2 deficiency abolishes the anticancer and pro-aging activity of short telomeres
Aging Cell, Vol. 8, Núm. 1, pp. 2-17
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TRF1 controls telomere length and mitotic fidelity in epithelial homeostasis
Molecular and Cellular Biology, Vol. 29, Núm. 6, pp. 1608-1625
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Telomere shortening relaxes X chromosome inactivation and forces global transcriptome alterations
Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Núm. 46, pp. 19393-19398
2008
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Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice
Cell, Vol. 135, Núm. 4, pp. 609-622
2007
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Deficient mismatch repair improves organismal fitness and survival of mice with dysfunctional telomeres
Genes and Development, Vol. 21, Núm. 17, pp. 2234-2247
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Delayed ageing through damage protection by the Arf/p53 pathway
Nature, Vol. 448, Núm. 7151, pp. 375-379
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Telomerase abrogation dramatically accelerates TRF2-induced epithelial carcinogenesis
Genes and Development, Vol. 21, Núm. 2, pp. 206-220
2006
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Increased p53 activity does not accelerate telomere-driven ageing
EMBO Reports, Vol. 7, Núm. 5, pp. 546-552
2005
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Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice
Oncogene, Vol. 24, Núm. 13, pp. 2256-2270
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The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression
EMBO Reports, Vol. 6, Núm. 3, pp. 268-274
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XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer
Nature Genetics, Vol. 37, Núm. 10, pp. 1063-1071
2004
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Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-tert mice
Molecular and Cellular Biology, Vol. 24, Núm. 10, pp. 4275-4293
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Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs
Journal of Cell Biology, Vol. 167, Núm. 4, pp. 627-638
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Shorter telomeres, accelerated ageing and increased lymphoma in DNA-PKcs-deficient mice
EMBO Reports, Vol. 5, Núm. 5, pp. 503-509