Caracterización fenotípica de animales modificados genéticamente
Centro Nacional de Biotecnología
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Centro Nacional de Biotecnología (22)
2015
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Distinct p21 requirements for regulating normal and self-reactive T cells through IFN-γ production
Scientific Reports, Vol. 5
2013
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Gadd45g Is Essential for Primary Sex Determination, Male Fertility and Testis Development
PLoS ONE, Vol. 8, Núm. 3
2010
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Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition
Molecular Cancer, Vol. 9
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Phosphatidylinositol 3-Kinase γ Inhibition Ameliorates Inflammation and Tumor Growth in a Model of Colitis-Associated Cancer
Gastroenterology, Vol. 138, Núm. 4, pp. 1374-1383
2007
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Normal cellular senescence and cancer susceptibility in mice genetically deficient in Ras-induced senescence-1 (Ris1)
Oncogene, Vol. 26, Núm. 12, pp. 1673-1680
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p21CIP1/WAF1 controls proliferation of activated/memory T cells and affects homeostasis and memory T cell responses
Journal of Immunology, Vol. 178, Núm. 4, pp. 2296-2306
2006
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Nucleocytoplasmic shuttling of STK16 (PKL12), a Golgi-resident serine/threonine kinase involved in VEGF expression regulation
Experimental Cell Research, Vol. 312, Núm. 2, pp. 135-144
2005
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Dido gene expression alterations are implicated in the induction of hematological myeloid neoplasms
Journal of Clinical Investigation, Vol. 115, Núm. 9, pp. 2351-2362
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Tumour biology: Senescence in premalignant tumours
Nature, Vol. 436, Núm. 7051, pp. 642
2004
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Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging
Genes and Development, Vol. 18, Núm. 22, pp. 2736-2746
2003
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Telomere Dysfunction Results in Enhanced Organismal Sensitivity to the Alkylating Agent N-Methyl-N-Nitrosourea
Cancer Research, Vol. 63, Núm. 21, pp. 7047-7050
2002
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'Super p53' mice exhibit enhanced DNA damage response, are tumor resistant and age normally
EMBO Journal, Vol. 21, Núm. 22, pp. 6225-6235
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Autocrine production of IFN-γ by macrophages controls their recruitment to kidney and the development of glomerulonephritis in MRL/lpr mice
Journal of Immunology, Vol. 169, Núm. 2, pp. 1058-1067
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Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development
Molecular and Cellular Biology, Vol. 22, Núm. 20, pp. 7291-7301
2001
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Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes
EMBO Journal, Vol. 20, Núm. 11, pp. 2619-2630
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Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres
EMBO Reports, Vol. 2, Núm. 9, pp. 800-807
2000
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Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo
FASEB Journal, Vol. 14, Núm. 7, pp. 895-903
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Limited overlapping roles of p15(INK4b) and p18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis
EMBO Journal, Vol. 19, Núm. 13, pp. 3496-3506
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Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals
Journal of Experimental Medicine, Vol. 192, Núm. 11, pp. 1625-1636
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Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis
Nature Genetics, Vol. 26, Núm. 1, pp. 114-117