Mecanismos moleculares de enfermedades infecciosas y neurodegenerativas
Universidad Autónoma de Madrid
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Universidad Autónoma de Madrid (39)
2022
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Hypothyroidism confers tolerance to cerebral malaria
Science advances, Vol. 8, Núm. 14, pp. eabj7110
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TNAP upregulation is a critical factor in Tauopathies and its blockade ameliorates neurotoxicity and increases life-expectancy
Neurobiology of Disease, Vol. 165
2021
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Kidins220 deficiency causes ventriculomegaly via SNX27-retromer-dependent AQP4 degradation
Molecular Psychiatry, Vol. 26, Núm. 11, pp. 6411-6426
2020
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Differential regulation of Kidins220 isoforms in Huntington's disease
Brain Pathology, Vol. 30, Núm. 1, pp. 120-136
2019
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Amyloid peptide induced neuroinflammation increases the P2X7 receptor expression in microglial cells, impacting on its functionality
Frontiers in Cellular Neuroscience, Vol. 13
2018
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Erratum: Author Correction: Excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1 (Nature communications (2017) 8 1 (2275))
Nature communications
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Haploinsufficient TNAP mice display decreased extracellular ATP levels and expression of Pannexin-1 channels
Frontiers in Pharmacology, Vol. 9, Núm. MAR
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MicroRNA-22 controls aberrant neurogenesis and changes in neuronal morphology after status epilepticus
Frontiers in Molecular Neuroscience, Vol. 11
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The regulation of proteostasis in glial cells by nucleotide receptors is key in acute neuroinflammation
FASEB Journal, Vol. 32, Núm. 6, pp. 3020-3032
2016
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Protein degradation in a LAMP-2-deficient B-lymphoblastoid cell line from a patient with Danon disease
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1862, Núm. 8, pp. 1423-1432
2015
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Tissue-nonspecific Alkaline Phosphatase Regulates Purinergic Transmission in the Central Nervous System during Development and Disease
Computational and Structural Biotechnology Journal, Vol. 13, pp. 95-100
2014
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Epitope mapping of antibodies to alpha-synuclein in LRRK2 mutation carriers, idiopathic parkinson disease patients, and healthy controls
Frontiers in Aging Neuroscience, Vol. 6, Núm. JUL
2013
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P2X receptors as targets for the treatment of status epilepticus
Frontiers in Cellular Neuroscience, Vol. 7, Núm. NOV
2012
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A critical appraisal of quantitative studies of protein degradation in the framework of cellular proteostasis
Biochemistry Research International
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Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation
Journal of Cell Science, Vol. 125, Núm. 1, pp. 176-188
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Tau overexpression results in its secretion via membrane vesicles
Neurodegenerative Diseases, Vol. 10, Núm. 1-4, pp. 73-75
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α-Synuclein accumulates in huntingtin inclusions but forms independent filaments and its deficiency attenuates early phenotype in a mouse model of Huntington's disease
Human Molecular Genetics, Vol. 21, Núm. 3, pp. 495-510
2011
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Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease
Brain, Vol. 134, Núm. 1, pp. 119-136
2010
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Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation
Journal of Neuroscience, Vol. 30, Núm. 10, pp. 3675-3688
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PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum
Cell Death and Differentiation, Vol. 17, Núm. 2, pp. 324-335