Publications by the researcher in collaboration with Antonio García García (27)

2013

  1. Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease

    Medicinal Research Reviews, Vol. 33, Núm. 1, pp. 139-189

2012

  1. Galantamine elicits neuroprotection by inhibiting iNOS, NADPH oxidase and ROS in hippocampal slices stressed with anoxia/reoxygenation

    Neuropharmacology, Vol. 62, Núm. 2, pp. 1082-1090

2011

  1. Chondroitin sulfate reduces cell death of rat hippocampal slices subjected to oxygen and glucose deprivation by inhibiting p38, NFκB and iNOS

    Neurochemistry International, Vol. 58, Núm. 6, pp. 676-683

  2. Effects of novel tacripyrines ITH12117 and ITH12118 on rat vas deferens contractions, calcium transients and cholinesterase activity

    European Journal of Pharmacology, Vol. 660, Núm. 2-3, pp. 411-419

  3. N-Acylaminophenothiazines: Neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 6, pp. 2224-2235

  4. Synthesis, structure, theoretical and experimental in vitro antioxidant/pharmacological properties of α-aryl, N-alkyl nitrones, as potential agents for the treatment of cerebral ischemia

    Bioorganic and Medicinal Chemistry, Vol. 19, Núm. 2, pp. 951-960

2010

  1. Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles

    Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 16, pp. 5861-5872

  2. Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives

    Journal of Medicinal Chemistry, Vol. 53, Núm. 14, pp. 5129-5143

2009

  1. Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease

    Journal of Medicinal Chemistry, Vol. 52, Núm. 9, pp. 2724-2732

2008

  1. New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 16, pp. 7759-7769

  2. Synthesis of 6-amino-1,4-dihydropyridines that prevent calcium overload and neuronal death

    European Journal of Medicinal Chemistry, Vol. 43, Núm. 3, pp. 668-674

2007

  1. An update on the pharmacology of galantamine

    Expert Opinion on Investigational Drugs, Vol. 16, Núm. 12, pp. 1987-1998

  2. Neuroprotectant minocycline depresses glutamatergic neurotransmission and Ca2+ signalling in hippocampal neurons

    European Journal of Neuroscience, Vol. 26, Núm. 9, pp. 2481-2495

2006

  1. Intermolecular silyl migration reactions

    Journal of Chemical Research, pp. 698-701

  2. New multipotent tetracyclic tacrines with neuroprotective activity

    Bioorganic and Medicinal Chemistry, Vol. 14, Núm. 24, pp. 8176-8185

  3. Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease

    Journal of Medicinal Chemistry, Vol. 49, Núm. 26, pp. 7607-7610

  4. Synthesis and biological evaluation of new 4H-pyrano[2,3-b]quinoline derivatives that block acetylcholinesterase and cell calcium signals, and cause neuroprotection against calcium overload and free radicals

    European Journal of Medicinal Chemistry, Vol. 41, Núm. 12, pp. 1464-1469

  5. Synthesis and pharmacology of Galantamine

    Chemical Reviews, Vol. 106, Núm. 1, pp. 116-133

  6. Unexpected results in the Friedländer reaction of 4-aryl-7,7-dimethyl- 5-oxo-5,6,7,8-tetrahydro-4H-[1]benzopyran-3-carbonitriles

    Journal of Chemical Research, pp. 536-538

2005

  1. 1,6-C-H and 1,5-O-Si insertion reactions of alkylidenecarbene derivatives of monosaccharides

    Journal of Carbohydrate Chemistry, Vol. 24, Núm. 4-6, pp. 369-377