Publications in collaboration with researchers from University of Bologna (12)

2021

  1. (±)- BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease

    ACS Chemical Neuroscience, Vol. 12, Núm. 8, pp. 1328-1342

2019

  1. Quinoxalinetacrine QT78, a cholinesterase inhibitor as a potential ligand for Alzheimer’s disease therapy

    Molecules, Vol. 24, Núm. 8

  2. Tacrines as Therapeutic Agents for Alzheimer's Disease. IV. The Tacripyrines and Related Annulated Tacrines

    Chemical Record, Vol. 19, Núm. 5, pp. 927-937

2018

  1. Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 155, pp. 839-846

2017

  1. 5-Methyl-: N -(8-(5,6,7,8-tetrahydroacridin-9-ylamino)octyl)-5 H -indolo[2,3- b] quinolin-11-amine: A highly potent human cholinesterase inhibitor

    MedChemComm, Vol. 8, Núm. 6, pp. 1307-1317

2016

  1. Imidazopyranotacrines as Non-Hepatotoxic, Selective Acetylcholinesterase Inhibitors, and Antioxidant Agents for Alzheimer's Disease Therapy

    Molecules, Vol. 21, Núm. 4

2015

  1. Novel tacrine-grafted ugi adducts as multipotent anti-alzheimer drugs: A synthetic renewal in tacrine-ferulic acid hybrids

    ChemMedChem, Vol. 10, Núm. 3, pp. 523-539

2013

  1. The bivalent ligand approach as a tool for improving the in vitro anti-alzheimer multitarget profile of dimebon

    ChemMedChem, Vol. 8, Núm. 8, pp. 1276-1281

2012

  1. Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: Synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine

    European Journal of Medicinal Chemistry, Vol. 52, pp. 251-262

2011

  1. Chemical and pharmacological studies on enantiomerically pure p-methoxytacripyrines, promising multi-target-directed ligands for the treatment of Alzheimer's disease

    ChemMedChem, Vol. 6, Núm. 11, pp. 1990-1997

  2. Synthesis and biological assessment of diversely substituted furo[2,3-b]quinolin-4-amine and pyrrolo[2,3-b]quinolin-4-amine derivatives, as novel tacrine analogues

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 12, pp. 6119-6130

2009

  1. Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease

    Journal of Medicinal Chemistry, Vol. 52, Núm. 9, pp. 2724-2732