Publicaciones en colaboración con investigadores/as de Universitat Autònoma de Barcelona (25)

2022

  1. Relationship between immunometabolic status and cognitive performance among major depression disorder patients

    Psychoneuroendocrinology, Vol. 137

2020

  1. Characterization of a cholesteronitrone (ISQ-201), a novel drug candidate for the treatment of ischemic stroke

    Antioxidants, Vol. 9, Núm. 4, pp. 1-21

2017

  1. Quinolinyl Nitrone RP19 Induces Neuroprotection after Transient Brain Ischemia

    ACS Chemical Neuroscience, Vol. 8, Núm. 10, pp. 2202-2213

  2. The proof-of-concept of ASS234: Peripherally administered ASS234 enters the central nervous system and reduces pathology in a male mouse model of Alzheimer disease

    Journal of Psychiatry and Neuroscience, Vol. 42, Núm. 1, pp. 59-69

2016

  1. Multi-target directed donepezil-like ligands for Alzheimer's disease

    Frontiers in Neuroscience, Vol. 10, Núm. MAY

2015

  1. CholesteroNitrones for Stroke

    Journal of Medicinal Chemistry, Vol. 58, Núm. 16, pp. 6704-6709

2014

  1. Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 75, pp. 82-95

  2. Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 80, pp. 543-561

2013

  1. A therapeutic approach to cerebrovascular diseases based on indole substituted hydrazides and hydrazines able to interact with human vascular adhesion protein-1, monoamine oxidases (A and B), AChE and BuChE

    Journal of Neural Transmission, Vol. 120, Núm. 6, pp. 911-918

  2. Analysis of the antioxidant properties of differently substituted 2- and 3-indolyl carbohydrazides and related derivatives

    European Journal of Medicinal Chemistry, Vol. 63, pp. 670-674

  3. The type II cGMP dependent protein kinase regulates GluA1 levels at the plasma membrane of developing cerebellar granule cells

    Biochimica et Biophysica Acta - Molecular Cell Research, Vol. 1833, Núm. 8, pp. 1820-1831

2012

  1. Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: Synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine

    European Journal of Medicinal Chemistry, Vol. 52, pp. 251-262

2011

  1. Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 9, pp. 4665-4668

  2. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(Benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease

    Journal of Medicinal Chemistry, Vol. 54, Núm. 24, pp. 8251-8270

2009

  1. PF9601N [N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine] confers MAO-B independent neuroprotection in ER stress-induced cell death

    Molecular and Cellular Neuroscience, Vol. 41, Núm. 1, pp. 19-31

2008

  1. Anti-apoptotic effect of Mao-B inhibitor PF9601N [N-(2-propynyl)-2-(5- benzyloxy-indolyl) methylamine] is mediated by p53 pathway inhibition in MPP+-treated SH-SY5Y human dopaminergic cells

    Journal of Neurochemistry, Vol. 105, Núm. 6, pp. 2404-2417

2003

  1. Protective effect of N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine (PF 9601N), a novel MAO-B inhibitor, on dopamine-lesioned PC12 cultured cells

    Journal of Pharmacy and Pharmacology, Vol. 55, Núm. 5, pp. 713-716

2002

  1. Synthesis and acetylcholinesterase/butyrylcholinesterase inhibition activity of 4-amino-2,3-diaryl- 5,6,7,8-tetrahydrofuro(and thieno)[2,3-b]-quinolines, and 4-amino-5,6,7,8,9-pentahydro-2,3-diphenylcyclohepta[e]furo(and thieno)-[2,3-b]pyridines

    Archiv der Pharmazie, Vol. 335, Núm. 7, pp. 347-353

2001

  1. Synthesis and acetylcholinesterase/butyrylcholinesterase inhibition activity of new tacrine-like analogues

    Bioorganic and Medicinal Chemistry, Vol. 9, Núm. 3, pp. 727-732

2000

  1. The CSIC reaction on substrates derived from aldehydes

    Tetrahedron, Vol. 56, Núm. 16, pp. 2523-2531