Publications en collaboration avec des chercheurs de Hospital Universitario 12 de Octubre (20)

2023

  1. Neuroprotective and antioxidant properties of new quinolylnitrones in in vitro and in vivo cerebral ischemia models

    Scientific Reports, Vol. 13, Núm. 1

2022

  1. Nucleobase-Derived Nitrones: Synthesis and Antioxidant and Neuroprotective Activities in an In Vitro Model of Ischemia–Reperfusion

    International Journal of Molecular Sciences, Vol. 23, Núm. 6

  2. Polyfunctionalized α-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment

    Antioxidants, Vol. 11, Núm. 9

  3. Synthesis and Antioxidant Properties of HeteroBisNitrones Derived from Benzene Dicarbaldehydes

    Antioxidants, Vol. 11, Núm. 8

2021

  1. Studies on the affinity of 6-[(: N -(cyclo)aminoalkyl)oxy]-4 H -chromen-4-ones for sigma 1/2 receptors

    RSC Medicinal Chemistry, Vol. 12, Núm. 6, pp. 1000-1004

  2. Synthesis, Neuroprotection, and Antioxidant Activity of 1,1'-Biphenylnitrones as α-Phenyl-N-tert-butylnitrone Analogues in In Vitro Ischemia Models

    Molecules (Basel, Switzerland), Vol. 26, Núm. 4

2020

  1. Acetylcholinesterase inhibition of diversely functionalized quinolinones for alzheimer’s disease therapy

    International Journal of Molecular Sciences, Vol. 21, Núm. 11, pp. 1-20

  2. Automated Synthesis of New Quinoxalinetacrines

    ChemistrySelect, Vol. 5, Núm. 21, pp. 6491-6493

  3. Homo-tris-nitrones derived from α-phenyl-n-tert-butylnitrone: Synthesis, neuroprotection and antioxidant properties

    International Journal of Molecular Sciences, Vol. 21, Núm. 21, pp. 1-18

  4. In Vitro and in Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases

    ACS Chemical Neuroscience, Vol. 11, Núm. 22, pp. 3793-3801

  5. Neuroprotection by phytoestrogens in the model of deprivation and resupply of oxygen and glucose in vitro: The contribution of autophagy and related signaling mechanisms

    Antioxidants, Vol. 9, Núm. 6, pp. 1-20

  6. Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models

    Scientific Reports, Vol. 10, Núm. 1

2019

  1. Synthesis and Neuroprotective Properties of N-Substituted C-Dialkoxyphosphorylated Nitrones

    ACS Omega, Vol. 4, Núm. 5, pp. 8581-8587

2018

  1. Contilisant, a Tetratarget Small Molecule for Alzheimer's Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile

    Journal of Medicinal Chemistry, Vol. 61, Núm. 15, pp. 6937-6943

  2. In silico assessment of the metabolism and its safety significance of multitarget propargylamine ASS234

    CNS Neuroscience and Therapeutics

  3. Modulation of Heat Shock Response Proteins by ASS234, Targeted for Neurodegenerative Diseases Therapy

    Chemical Research in Toxicology, Vol. 31, Núm. 9, pp. 839-842

  4. Neuroinflammation Signaling Modulated by ASS234, a Multitarget Small Molecule for Alzheimer's Disease Therapy

    ACS Chemical Neuroscience, Vol. 9, Núm. 12, pp. 2880-2885

2017

  1. 5-Methyl-: N -(8-(5,6,7,8-tetrahydroacridin-9-ylamino)octyl)-5 H -indolo[2,3- b] quinolin-11-amine: A highly potent human cholinesterase inhibitor

    MedChemComm, Vol. 8, Núm. 6, pp. 1307-1317

  2. Corrigendum: Melatonin and nitrones as potential therapeutic agents for stroke [Front. Aging Neurosci., 8 (2016) (281)] DOI:10.3389/fnagi.2016.00281

    Frontiers in Aging Neuroscience

2016

  1. Melatonin and nitrones as potential therapeutic agents for stroke

    Frontiers in Aging Neuroscience, Vol. 8, Núm. NOV