Publicaciones en colaboración con investigadores/as de Instituto de Química Médica (30)

2021

  1. Promising hit compounds against resistant trichomoniasis: Synthesis and antiparasitic activity of 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles

    Bioorganic and Medicinal Chemistry Letters, Vol. 37

2018

  1. Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines

    ChemMedChem, Vol. 13, Núm. 12, pp. 1246-1259

  2. Drug repositioning for novel antitrichomonas from known antiprotozoan drugs using hierarchical screening

    Future Medicinal Chemistry, Vol. 10, Núm. 8, pp. 863-878

2016

  1. Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles

    European Journal of Medicinal Chemistry, Vol. 115, pp. 295-310

  2. In vitro trichomonacidal activity and preliminary in silico chemometric studies of 5-nitroindazolin-3-one and 3-alkoxy-5-nitroindazole derivatives

    Parasitology, Vol. 143, Núm. 1, pp. 34-40

2015

  1. Synthesis and in vitro and in vivo biological evaluation of substituted nitroquinoxalin-2-ones and 2,3-diones as novel trichomonacidal agents

    European Journal of Medicinal Chemistry, Vol. 94, pp. 276-283

2014

  1. A sequential procedure for rapid and accurate identification of putative trichomonacidal agents

    Journal of Microbiological Methods, Vol. 105, pp. 162-167

  2. Antiprotozoan lead discovery by aligning dry and wet screening: Prediction, synthesis, and biological assay of novel quinoxalinones

    Bioorganic and Medicinal Chemistry, Vol. 22, Núm. 5, pp. 1568-1585

  3. Determination of internal transcribed spacer regions (ITS) in Trichomonas vaginalis isolates and differentiation among Trichomonas species

    Parasitology International, Vol. 63, Núm. 2, pp. 427-431

2009

  1. Discovery of novel trichomonacidals using LDA-driven QSAR models and bond-based bilinear indices as molecular descriptors

    QSAR and Combinatorial Science, Vol. 28, Núm. 1, pp. 9-26

2008

  1. Bond-based linear indices in QSAR: Computational discovery of novel anti-trichomonal compounds

    Journal of Computer-Aided Molecular Design, Vol. 22, Núm. 8, pp. 523-540

  2. New antitrichomonal drug-like chemicals selected by bond (edge)-based TOMOCOMD-CARDD descriptors

    Journal of Biomolecular Screening, Vol. 13, Núm. 8, pp. 785-794

2006

  1. Antiparasitic properties of homoallylamines and related compounds

    Acta Parasitologica, Vol. 51, Núm. 1, pp. 73-78

  2. New ligand-based approach for the discovery of antitrypanosomal compounds

    Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 7, pp. 1898-1904

  3. Non-stochastic quadratic fingerprints and LDA-based QSAR models in hit and lead generation through virtual screening: theoretical and experimental assessment of a promising method for the discovery of new antimalarial compounds

    European Journal of Medicinal Chemistry, Vol. 41, Núm. 4, pp. 483-493

  4. Predicting antitrichomonal activity: A computational screening using atom-based bilinear indices and experimental proofs

    Bioorganic and Medicinal Chemistry, Vol. 14, Núm. 19, pp. 6502-6524

2005

  1. A computer-based approach to the rational discovery of new trichomonacidal drugs by atom-type linear indices

    Current Drug Discovery Technologies, Vol. 2, Núm. 4, pp. 245-265

  2. A linear discrimination analysis based virtual screening of trichomonacidal lead-like compounds: Outcomes of in silico studies supported by experimental results

    Bioorganic and Medicinal Chemistry Letters, Vol. 15, Núm. 17, pp. 3838-3843

  3. Synthesis and antiparasitic properties of new 4-N-benzylamino-4-hetarylbut- 1-enes

    Archiv der Pharmazie, Vol. 338, Núm. 1, pp. 32-37

  4. Synthesis and biological properties of new 5-nitroindazole derivatives

    Bioorganic and Medicinal Chemistry, Vol. 13, Núm. 9, pp. 3197-3207