Química de sistemas insaturados y heterociclos bioactivos
Instituto de Química Orgánica General
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Instituto de Química Orgánica General (199)
2024
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Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases
Journal of Medicinal Chemistry, Vol. 67, Núm. 18, pp. 16533-16555
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Gold-Catalyzed Orthogonal and Chemocontrolled Synthesis of [4-7-6] Tricycles from 1,5-Diynes
Advanced Synthesis and Catalysis
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The proof of concept of 2-{3-[N-(1-benzylpiperidin-4-yl)propyl]amino}-6-[N-methyl-N-(prop-2-yn-1-yl)amino]-4-phenylpyridine-3,5-dicarbonitrile for the therapy of neuropathic pain
Bioorganic Chemistry, Vol. 150
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Unveiling the Use of 1,1-Bis(triflyl)ethylene as CF3SO2CH═CH2 Source with the Assistance of (n-Bu)4NF: Synthesis of 3-[(Trifluoromethyl)sulfonyl]cyclobut-1-enes
Organic Letters, Vol. 26, Núm. 21, pp. 4560-4565
2023
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Highlighting the Rich Chemistry of the Allenone Moiety
Advanced Synthesis and Catalysis, Vol. 365, Núm. 9, pp. 1332-1384
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Indium-promoted butenolide synthesis through consecutive C-C and C-O bond formations in aqueous tetrahydrofuran enabled by radicals
Organic Chemistry Frontiers, Vol. 10, Núm. 7, pp. 1773-1779
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Regioselectivity Control in the Synthesis of Linear Conjugated Dienes Enabled by Manganese(I)-Catalyzed C-H Activation
ACS Catalysis, Vol. 13, Núm. 22, pp. 14523-14529
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Straightforward Synthesis of Bis[(trifluoromethyl)sulfonyl]ethylated Isocoumarins from 2-Ethynylbenzoates
Journal of Organic Chemistry, Vol. 88, Núm. 11, pp. 7373-7380
2022
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2,3-Diodocarbazoles by a Domino Iodocyclization/Iodo-Translocation of (3-Iodoindolyl)butynols
Advanced Synthesis and Catalysis, Vol. 364, Núm. 22, pp. 3954-3959
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Au(I) as a π-Lewis Base Catalyst: Controlled Synthesis of Sterically Congested Bis(triflyl)enals from α-Allenols
ACS Catalysis, Vol. 12, Núm. 19, pp. 11675-11681
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Regioselectivity Switch Based on the Stoichiometry: Stereoselective Synthesis of Trisubstituted Vinyl Epoxides by Cu-Catalyzed 3-exo-trig Cyclization of α-Allenols
Advanced Synthesis and Catalysis, Vol. 364, Núm. 18, pp. 3289-3294
2021
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A Convenient Formal [4+2] Heterocylization Route to Bis(triflyl)tetrahydroquinolines
Chemistry - A European Journal, Vol. 27, Núm. 54, pp. 13534-13538
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Deciphering the Chameleonic Chemistry of Allenols: Breaking the Taboo of a Onetime Esoteric Functionality
Chemical Reviews, Vol. 121, Núm. 7, pp. 4193-4252
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Metal-Catalyzed Reactivity Reversal in the Sulfonylation Reaction of α-Allenols: Controlled Synthesis of 4-(Arylsulfonyl)-2,5-Dihydrofurans
Advanced Synthesis and Catalysis, Vol. 363, Núm. 16, pp. 3952-3956
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Metal-Free C-C/C-N/C-C Bond Formation Cascade for the Synthesis of (Trifluoromethyl)sulfonylated Cyclopenta[ b]indolines
Organic Letters, Vol. 23, Núm. 8, pp. 2921-2926
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Palladium-Catalyzed Hydroarylation of Homopropargyl Iodoindoles with Concurrent Alkyl and Iodonium Migrations
Advanced Synthesis and Catalysis, Vol. 363, Núm. 5, pp. 1449-1456
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Pd-catalyzed C(sp3)-C(sp) bond formation in iodocyclobutenes
Chemical Communications, Vol. 57, Núm. 68, pp. 8456-8459
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SYNTHESIS OF CARBAZOLES AND DERIVATIVES FROM ALLENES
Targets in Heterocyclic Systems, Vol. 25, pp. 409-423
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Synthesis of Polycyclic Aromatic Hydrocarbons Decorated by Fluorinated Carbon Acids/Carbanions
Chemistry - A European Journal, Vol. 27, Núm. 65, pp. 16112-16116
2020
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A catalyst-free bis(triflyl)ethylation/benzannulation reaction: Rapid access to carbazole-based superacidic carbon acids from alkynols
Chemical Communications, Vol. 56, Núm. 12, pp. 1795-1798