SANDRA
RODRÍGUEZ PERALES
Profesora asociada
Universitat de Barcelona
Barcelona, EspañaPublicaciones en colaboración con investigadores/as de Universitat de Barcelona (20)
2023
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A human genome editing–based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features
Blood, Vol. 142, Núm. 20, pp. 1752-1756
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Comprehensive characterization of a novel, oncogenic and targetable SEPTIN6::ABL2 fusion in T-ALL
British Journal of Haematology
2022
2021
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Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture
Nature Communications, Vol. 12, Núm. 1
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Alterations in slc4a2, slc26a7 and slc26a9 drive acid–base imbalance in gastric neuroendocrine tumors and uncover a novel mechanism for a co-occurring polyautoimmune scenario
Cells, Vol. 10, Núm. 12
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Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects
Scientific Reports, Vol. 11, Núm. 1
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Targeting OGG1 arrests cancer cell proliferation by inducing replication stress
Nucleic Acids Research, Vol. 48, Núm. 21, pp. 12234-12251
2020
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Impaired condensin complex and Aurora B kinase underlie mitotic and chromosomal defects in hyperdiploid B-cell ALL
Blood, Vol. 136, Núm. 3, pp. 313-327
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In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells
Nature Communications, Vol. 11, Núm. 1
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RIAM-VASP Module Relays Integrin Complement Receptors in Outside-In Signaling Driving Particle Engulfment
Cells, Vol. 9, Núm. 5
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Robustness of Catalytically Dead Cas9 Activators in Human Pluripotent and Mesenchymal Stem Cells
Molecular Therapy - Nucleic Acids, Vol. 20, pp. 196-204
2019
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Immune profiling and quantitative analysis decipher the clinical role of immune-checkpoint expression in the tumor immune microenvironment of DLBCL
Cancer Immunology Research, Vol. 7, Núm. 4, pp. 644-657
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NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia
Cell Stem Cell, Vol. 25, Núm. 5, pp. 607-621.e7
2018
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CRISPR/Cas9 for cancer therapy: Hopes and challenges
Biomedicines, Vol. 6, Núm. 4
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Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis
Molecular Cancer
2017
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Efficient Recreation of t(11;22) EWSR1-FLI1+ in Human Stem Cells Using CRISPR/Cas9
Stem Cell Reports, Vol. 8, Núm. 5, pp. 1408-1420
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Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the “safe harbor” AAVS1 locus
Stem Cell Research, Vol. 21, pp. 137-140
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Modeling mixed-lineage-rearranged leukemia initiation in CD34+ cells: A “CRISPR” solution
Haematologica
2016
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Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency
Stem Cell Reports, Vol. 7, Núm. 4, pp. 602-618
2015
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A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li-Fraumeni-like families
Nature Communications, Vol. 6