MERCEDES
OÑADERRA SÁNCHEZ
Investigadora hasta 2022
FRANCISCO JAVIER
LACADENA GARCÍA-GALLO
Profesor titular de universidad
Publicaciones en las que colabora con FRANCISCO JAVIER LACADENA GARCÍA-GALLO (38)
2017
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Fungal ribotoxins: A review of potential biotechnological applications
Toxins, Vol. 9, Núm. 2
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Minimized natural versions of fungal ribotoxins show improved active site plasticity
Archives of Biochemistry and Biophysics, Vol. 619, pp. 45-53
2016
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Involvement of loop 5 lysine residues and the N-terminal β-hairpin of the ribotoxin hirsutellin A on its insecticidal activity
Biological Chemistry, Vol. 397, Núm. 2, pp. 135-145
2015
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Involvement of loops 2 and 3 of α-sarcin on its ribotoxic activity
Toxicon, Vol. 96, pp. 1-9
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Preparation of an engineered safer immunotoxin against colon carcinoma based on the ribotoxin hirsutellin A
FEBS Journal, Vol. 282, Núm. 11, pp. 2131-2141
2013
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Hirsutellin A: A paradigmatic example of the insecticidal function of fungal ribotoxins
Insects, Vol. 4, Núm. 3, pp. 339-356
2012
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A non-cytotoxic but ribonucleolytically specific ribotoxin variant: Implication of tryptophan residues in the cytotoxicity of hirsutellin A
Biological Chemistry, Vol. 393, Núm. 6, pp. 449-456
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Implication of an Asp residue in the ribonucleolytic activity of hirsutellin A reveals new electrostatic interactions at the active site of ribotoxins
Biochimie, Vol. 94, Núm. 2, pp. 427-433
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Production and characterization of a colon cancer-specific immunotoxin based on the fungal ribotoxin α-sarcin
Protein Engineering, Design and Selection, Vol. 25, Núm. 8, pp. 425-435
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Production and characterization of scFvA33T1, an immunoRNase targeting colon cancer cells
FEBS Journal, Vol. 279, Núm. 17, pp. 3022-3032
2008
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The insecticidal protein hirsutellin A from the mite fungal pathogen Hirsutella thompsonii is a ribotoxin
Proteins: Structure, Function and Genetics, Vol. 72, Núm. 1, pp. 217-228
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The therapeutic potential of fungal ribotoxins
Current Pharmaceutical Biotechnology, Vol. 9, Núm. 3, pp. 153-160
2007
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Fungal ribotoxins: Molecular dissection of a family of natural killers
FEMS Microbiology Reviews, Vol. 31, Núm. 2, pp. 212-237
2005
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Anomalous electrophoretic behavior of a very acidic protein: Ribonuclease U2
Electrophoresis, Vol. 26, Núm. 18, pp. 3407-3413
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Production and characterization of a noncytotoxic deletion variant of the Aspergillus fumigatus allergen Aspf1 displaying reduced IgE binding
FEBS Journal, Vol. 272, Núm. 10, pp. 2536-2544
2001
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Arginine 121 is a crucial residue for the specific cytotoxic activity of the ribotoxin α-sarcin
European Journal of Biochemistry, Vol. 268, Núm. 23, pp. 6190-6196
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Involvement of the amino-terminal β-hairpin of the Aspergillus ribotoxins on the interaction with membranes and nonspecific ribonuclease activity
Protein Science, Vol. 10, Núm. 8, pp. 1658-1668
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RNase U2 and α-sarcin: A study of relationships
Methods in Enzymology (Academic Press Inc.), pp. 335-351
2000
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Assignment of the contribution of the tryptophan residues to the spectroscopic and functional properties of the ribotoxin α-Sarcin
Proteins: Structure, Function and Genetics, Vol. 41, Núm. 3, pp. 350-361
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Overproduction in Escherichia coli and purification of the hemolytic protein sticholysin II from the sea anemone Stichodactyla helianthus
Protein Expression and Purification, Vol. 18, Núm. 1, pp. 71-76