MERCEDES
OÑADERRA SÁNCHEZ
Chercheuse jusqu' 2022
LUCÍA
GARCÍA ORTEGA
Profesora titular de universidad
Publications dans lesquelles il/elle collabore avec LUCÍA GARCÍA ORTEGA (18)
2017
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Fungal ribotoxins: A review of potential biotechnological applications
Toxins, Vol. 9, Núm. 2
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Minimized natural versions of fungal ribotoxins show improved active site plasticity
Archives of Biochemistry and Biophysics, Vol. 619, pp. 45-53
2016
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Involvement of loop 5 lysine residues and the N-terminal β-hairpin of the ribotoxin hirsutellin A on its insecticidal activity
Biological Chemistry, Vol. 397, Núm. 2, pp. 135-145
2015
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Involvement of loops 2 and 3 of α-sarcin on its ribotoxic activity
Toxicon, Vol. 96, pp. 1-9
2013
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Fungal extracellular ribotoxins as insecticidal agents
Insect Biochemistry and Molecular Biology, Vol. 43, Núm. 1, pp. 39-46
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Hirsutellin A: A paradigmatic example of the insecticidal function of fungal ribotoxins
Insects, Vol. 4, Núm. 3, pp. 339-356
2012
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A non-cytotoxic but ribonucleolytically specific ribotoxin variant: Implication of tryptophan residues in the cytotoxicity of hirsutellin A
Biological Chemistry, Vol. 393, Núm. 6, pp. 449-456
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Implication of an Asp residue in the ribonucleolytic activity of hirsutellin A reveals new electrostatic interactions at the active site of ribotoxins
Biochimie, Vol. 94, Núm. 2, pp. 427-433
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Production and characterization of a colon cancer-specific immunotoxin based on the fungal ribotoxin α-sarcin
Protein Engineering, Design and Selection, Vol. 25, Núm. 8, pp. 425-435
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Production and characterization of scFvA33T1, an immunoRNase targeting colon cancer cells
FEBS Journal, Vol. 279, Núm. 17, pp. 3022-3032
2007
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Fungal ribotoxins: Molecular dissection of a family of natural killers
FEMS Microbiology Reviews, Vol. 31, Núm. 2, pp. 212-237
2005
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Anomalous electrophoretic behavior of a very acidic protein: Ribonuclease U2
Electrophoresis, Vol. 26, Núm. 18, pp. 3407-3413
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Production and characterization of a noncytotoxic deletion variant of the Aspergillus fumigatus allergen Aspf1 displaying reduced IgE binding
FEBS Journal, Vol. 272, Núm. 10, pp. 2536-2544
2004
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Conserved asparagine residue 54 of α-sarcin plays a role in protein stability and enzyme activity
Biological Chemistry, Vol. 385, Núm. 12, pp. 1165-1170
2003
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Leucine 145 of the ribotoxin α-sarcin plays a key role for determining the specificity of the ribosome-inactivating activity of the protein
Protein Science, Vol. 12, Núm. 1, pp. 161-169
2001
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Involvement of the amino-terminal β-hairpin of the Aspergillus ribotoxins on the interaction with membranes and nonspecific ribonuclease activity
Protein Science, Vol. 10, Núm. 8, pp. 1658-1668
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RNase U2 and α-sarcin: A study of relationships
Methods in Enzymology (Academic Press Inc.), pp. 335-351
2000
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Ribonuclease U2: Cloning, production in Pichia pastoris and affinity chromatography purification of the active recombinant protein
FEMS Microbiology Letters, Vol. 189, Núm. 2, pp. 165-169