JOSÉ GREGORIO
GAVILANES FRANCO
Investigador ata 2022
Jose Manuel
Perez Cañadillas
Publicacións nas que colabora con Jose Manuel Perez Cañadillas (7)
2003
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Dissecting Structural and Electrostatic Interactions of Charged Groups in α-Sarcin. An NMR Study of Some Mutants Involving the Catalytic Residues
Biochemistry, Vol. 42, Núm. 45, pp. 13122-13133
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Leucine 145 of the ribotoxin α-sarcin plays a key role for determining the specificity of the ribosome-inactivating activity of the protein
Protein Science, Vol. 12, Núm. 1, pp. 161-169
2002
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Backbone dynamics of the cytotoxic ribonuclease α-sarchin by 15N NMR relaxation methods
Journal of Biomolecular NMR, Vol. 24, Núm. 4, pp. 301-316
2000
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Assignment of the contribution of the tryptophan residues to the spectroscopic and functional properties of the ribotoxin α-Sarcin
Proteins: Structure, Function and Genetics, Vol. 41, Núm. 3, pp. 350-361
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The highly refined solution structure of the cytotoxic ribonuclease α-Sarcin reveals the structural requirements for substrate recognition and ribonucleolytic activity
Journal of Molecular Biology, Vol. 299, Núm. 4, pp. 1061-1073
1999
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Role of histidine-50, glutamic acid-96, and histidine-137 in the ribonucleolytic mechanism of the ribotoxin α-sarcin
Proteins: Structure, Function and Genetics, Vol. 37, Núm. 3, pp. 474-484
1998
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Characterization of pK(a) values and titration shifts in the cytotoxic ribonuclease α-sarcin by NMR. Relationship between electrostatic interactions, structure, and catalytic function
Biochemistry, Vol. 37, Núm. 45, pp. 15865-15876