SILVIA
ORTEGA GUTIÉRREZ
Catedrática de universidad
Alma
Viso Beronda
Publications dans lesquelles il/elle collabore avec Alma Viso Beronda (17)
2017
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Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling
Chemistry - A European Journal, Vol. 23, Núm. 7, pp. 1676-1685
2011
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Development of non-peptide ligands of growth factor receptor-bound protein 2-src homology 2 domain using molecular modeling and NMR spectroscopy
Journal of Medicinal Chemistry, Vol. 54, Núm. 4, pp. 1096-1100
2010
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Development of fluorescent ligands for the human 5-HT1A receptor
ACS Medicinal Chemistry Letters, Vol. 1, Núm. 6, pp. 249-253
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Development of molecular probes for the human 5-HT6 receptor
Journal of Medicinal Chemistry, Vol. 53, Núm. 19, pp. 7095-7106
2008
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The medicinal chemistry of agents targeting monoacylglycerol lipase
Current Topics in Medicinal Chemistry, Vol. 8, Núm. 3, pp. 231-246
2005
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Activation of the endocannabinoid system as therapeutic approach in a murine model of multiple sclerosis
FASEB Journal, Vol. 19, Núm. 10, pp. 1338-1340
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Involvement of cannabinoids in cellular proliferation
Mini-Reviews in Medicinal Chemistry
2004
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Characterization of an anandamide degradation system in prostate epithelial PC-3 cells: Synthesis of new transporter inhibitors as tools for this study
British Journal of Pharmacology, Vol. 141, Núm. 3, pp. 457-467
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Comparison of anandamide transport in FAAH wild-type and knockout neurons: Evidence for contributions by both FAAH and the CB1 receptor to anandamide uptake
Biochemistry, Vol. 43, Núm. 25, pp. 8184-8190
2003
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Design, synthesis and biological evaluation of new endocannabinoid transporter inhibitors
European Journal of Medicinal Chemistry
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Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: Comparison with effects on fatty acid amidohydrolase
Journal of Medicinal Chemistry, Vol. 46, Núm. 8, pp. 1512-1522
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Inhibition of fatty acid amidohydrolase, the enzyme responsible for the metabolism of the endocannabinoid anandamide, by analogues of arachidonoyl-serotonin
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 18, Núm. 3, pp. 225-231
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VR1 receptor modulators as potential drugs for neuropathic pain.
Mini reviews in medicinal chemistry, Vol. 3, Núm. 7, pp. 729-748
2002
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Endocannabinoid transporter inhibitors
Current Medicinal Chemistry - Central Nervous System Agents, Vol. 2, Núm. 2, pp. 129-141
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UCM707, a potent and selective inhibitor of endocannabinoid uptake, potentiates hypokinetic and antinociceptive effects of anandamide
European Journal of Pharmacology, Vol. 449, Núm. 1-2, pp. 99-103
2001
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Design, synthesis and biological evaluation of novel arachidonic acid derivatives as highly potent and selective endocannabinoid transporter inhibitors
Journal of Medicinal Chemistry, Vol. 44, Núm. 26, pp. 4505-4508
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Nuevas tendencias en la utilidad terapeútica de los cannabinoides
Anales de Química de la RSEQ, Núm. 2, pp. 14-21