SILVIA
ORTEGA GUTIÉRREZ
Catedrática de universidad
Publicaciones (71) Publicaciones de SILVIA ORTEGA GUTIÉRREZ
2024
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A new fluorescent probe for the visualization of progerin
Bioorganic Chemistry, Vol. 142
2023
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New Pharmacological Approaches for Rare Diseases
International Journal of Molecular Sciences
2022
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New Trends in Aging Drug Discovery
Biomedicines, Vol. 10, Núm. 8
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Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice
Journal of Medicinal Chemistry, Vol. 65, Núm. 16, pp. 10956-10974
2021
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Chemistry for the Identification of Therapeutic Targets: Recent Advances and Future Directions
European Journal of Organic Chemistry, Vol. 2021, Núm. 9, pp. 1307-1320
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Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson-Gilford Progeria Syndrome
ACS Central Science, Vol. 7, Núm. 8, pp. 1300-1310
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Small-molecule therapeutic perspectives for the treatment of progeria
International Journal of Molecular Sciences, Vol. 22, Núm. 13
2020
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A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration
Journal of Medicinal Chemistry, Vol. 63, Núm. 5, pp. 2372-2390
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Serum endocannabinoid levels in suicide attempters: A pilot study
European Neuropsychopharmacology, Vol. 40, pp. 52-60
2019
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A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia
Journal of Medicinal Chemistry, Vol. 62, Núm. 13, pp. 6035-6046
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Astroglial monoacylglycerol lipase controls mutant huntingtin-induced damage of striatal neurons
Neuropharmacology, Vol. 150, pp. 134-144
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Blocking Ras inhibition as an antitumor strategy
Seminars in Cancer Biology, Vol. 54, pp. 91-100
2018
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Development of a Fluorescent Bodipy Probe for Visualization of the Serotonin 5-HT
1A
Receptor in Native Cells of the Immune System
Bioconjugate Chemistry, Vol. 29, Núm. 6, pp. 2021-2027
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2-AG limits Theiler's virus induced acute neuroinflammation by modulating microglia and promoting MDSCs
GLIA, Vol. 66, Núm. 7, pp. 1447-1463
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A Fluorescent Probe to Unravel Functional Features of Cannabinoid Receptor CB1 in Human Blood and Tonsil Immune System Cells
Bioconjugate Chemistry, Vol. 29, Núm. 2, pp. 382-389
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Chapter 9: Fluorescent Probes in Medicinal Chemistry
RSC Drug Discovery Series (Royal Society of Chemistry), pp. 239-262
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Deregulation of the endocannabinoid system and therapeutic potential of ABHD6 blockade in the cuprizone model of demyelination
Biochemical Pharmacology, Vol. 157, pp. 189-201
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Monoacylglycerol lipase (MAGL) as a promising therapeutic target
Biochemical Pharmacology, Vol. 157, pp. 18-32
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Unique pharmacological properties of serotoninergic G-protein coupled receptors from cestodes
PLoS Neglected Tropical Diseases, Vol. 12, Núm. 2
2017
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2-arachidonoylglycerol reduces proteoglycans and enhances remyelination in a progressive model of demyelination
Journal of Neuroscience, Vol. 37, Núm. 35, pp. 8385-8398