MARÍA DEL HENAR
VÁZQUEZ VILLA
Profesora contratada doctora
Publicaciones (36) Publicaciones de MARÍA DEL HENAR VÁZQUEZ VILLA
2023
2022
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2-(Fluoromethoxy)-4′-(S-methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D1Receptor for Parkinson's Disease
Journal of Medicinal Chemistry, Vol. 65, Núm. 18, pp. 12256-12272
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Discovery of V-0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor toward Oral Treatment for "diabesity"
Journal of Medicinal Chemistry, Vol. 65, Núm. 7, pp. 5449-5461
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New Trends in Aging Drug Discovery
Biomedicines, Vol. 10, Núm. 8
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Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice
Journal of Medicinal Chemistry, Vol. 65, Núm. 16, pp. 10956-10974
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The Search for Antibacterial Inhibitors Targeting Cell Division Protein FtsZ at Its Nucleotide and Allosteric Binding Sites
Biomedicines, Vol. 10, Núm. 8
2021
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Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery
Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 5730-5745
2020
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A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration
Journal of Medicinal Chemistry, Vol. 63, Núm. 5, pp. 2372-2390
2019
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Allosteric modulators targeting GPCRs
GPCRs: Structure, Function, and Drug Discovery (Elsevier), pp. 195-241
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Progress toward allosteric ligands of metabotropic glutamate 7 (mGlu7) receptor: 2008-present
MedChemComm, Vol. 10, Núm. 2, pp. 326-331
2017
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A Positive Allosteric Modulator of the Serotonin 5-HT2C Receptor for Obesity
Journal of Medicinal Chemistry, Vol. 60, Núm. 23, pp. 9575-9584
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A new serotonin 5-HT 6 receptor antagonist with procognitive activity - Importance of a halogen bond interaction to stabilize the binding
Scientific Reports, Vol. 7
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Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling
Chemistry - A European Journal, Vol. 23, Núm. 7, pp. 1676-1685
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The structural assembly switch of cell division protein FtsZ probed with fluorescent allosteric inhibitors
Chemical Science, Vol. 8, Núm. 2, pp. 1525-1534
2016
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Chemoproteomic approach to explore the target profile of GPCR ligands: Application to 5-HT1A and 5-HT6 receptors
Chemistry - A European Journal, Vol. 22, Núm. 4, pp. 1313-1321
2015
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A Basal Tone of 2-Arachidonoylglycerol Contributes to Early Oligodendrocyte Progenitor Proliferation by Activating Phosphatidylinositol 3-Kinase (PI3K)/AKT and the Mammalian Target of Rapamycin (MTOR) Pathways
Journal of Neuroimmune Pharmacology, Vol. 10, Núm. 2, pp. 309-317
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Effective GTP-replacing FtsZ inhibitors and antibacterial mechanism of action
ACS Chemical Biology, Vol. 10, Núm. 3, pp. 834-843
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New inhibitors of angiogenesis with antitumor activity in vivo
Journal of Medicinal Chemistry, Vol. 58, Núm. 9, pp. 3757-3766
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Role of cannabinoid receptor CB<inf>2</inf> in HER2 pro-oncogenic signaling in breast cancer
Journal of the National Cancer Institute, Vol. 107, Núm. 6
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The status of the lysophosphatidic acid receptor type 1 (LPA<inf>1</inf>R)
MedChemComm, Vol. 6, Núm. 1, pp. 13-23