Publicaciones (24) Publicaciones de GABRIEL PIEDRAFITA FERNÁNDEZ

2024

  1. Organismal metabolism regulates the expansion of oncogenic PIK3CA mutant clones in normal esophagus

    Nature Genetics

  2. Self-sustaining long-term 3D epithelioid cultures reveal drivers of clonal expansion in esophageal epithelium

    Nature Genetics

2023

  1. Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth

    Nature Genetics, Vol. 55, Núm. 2, pp. 232-245

  2. Pseudoalignment tools as an efficient alternative to detect repeated transposable elements in scRNAseq data

    Bioinformatics (Oxford, England), Vol. 39, Núm. 1

2021

  1. Cysteine and iron accelerate the formation of ribose-5-phosphate, providing insights into the evolutionary origins of the metabolic network structure

    PLoS Biology, Vol. 19, Núm. 12

  2. Mutant clones in normal epithelium outcompete and eliminate emerging tumours

    Nature, Vol. 598, Núm. 7881, pp. 510-514

2020

  1. A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice

    Nature Communications, Vol. 11, Núm. 1

  2. Mutations in non-tumoral human urothelium: Disease prelude or epilogue?

    Bladder Cancer, Vol. 6, Núm. 3, pp. 249-252

  3. Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium

    Nature Genetics, Vol. 52, Núm. 6, pp. 604-614

2019

  1. Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation

    Cell Stem Cell, Vol. 25, Núm. 3, pp. 329-341.e6

2018

  1. Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations

    Cell Stem Cell, Vol. 23, Núm. 5, pp. 687-699.e8

2017

  1. Nonenzymatic gluconeogenesis-like formation of fructose 1,6-bisphosphate in ice

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Núm. 28, pp. 7403-7407

  2. Permeability-driven selection in a semi-empirical protocell model: The roots of prebiotic systems evolution

    Scientific Reports, Vol. 7, Núm. 1

2016

  1. Identifying ultrasensitive HGF dose-response functions in a 3D mammalian system for synthetic morphogenesis

    Scientific Reports, Vol. 6, Núm. 1

2015

  1. The impact of non-enzymatic reactions and enzyme promiscuity on cellular metabolism during (Oxidative) stress conditions

    Biomolecules, Vol. 5, Núm. 3, pp. 2101-2122

  2. The widespread role of non-enzymatic reactions in cellular metabolism

    Current Opinion in Biotechnology, Vol. 34, pp. 153-161

2013

  1. Simulating a Model of Metabolic Closure

    Biological Theory, Vol. 8, Núm. 4, pp. 383-390

2012

  1. Size matters: Influence of stochasticity on the self-maintenance of a simple model of metabolic closure

    Journal of Theoretical Biology, Vol. 300, pp. 143-151

  2. Viability conditions for a compartmentalized protometabolic system: A semi-empirical approach

    PLoS ONE, Vol. 7, Núm. 6

2011

  1. On the transition from prebiotic to proto-biological membranes: From 'self-assembly' to 'self-production'

    Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)