MANUEL
GUZMÁN PASTOR
Catedrático de universidad
Arkaitz
Carracedo Pérez
Arkaitz Carracedo Pérez-rekin lankidetzan egindako argitalpenak (20)
2015
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Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation
Cell Death and Differentiation, Vol. 22, Núm. 1, pp. 131-144
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TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling
Molecular and Cellular Oncology, Vol. 2, Núm. 3
2011
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Stimulation of ALK by the growth factor midkine renders glioma cells resistant to autophagy-mediated cell death
Autophagy, Vol. 7, Núm. 9, pp. 1071-1073
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Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action
Cell Death and Differentiation, Vol. 18, Núm. 6, pp. 959-973
2009
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Amphiregulin is a factor for resistance of glioma cells to cannabinoid-induced apoptosis
GLIA, Vol. 57, Núm. 13, pp. 1374-1385
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Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
Journal of Clinical Investigation, Vol. 119, Núm. 5, pp. 1359-1372
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Cannabinoids as potential antitumoral agents in pancreatic cancer
Pancreatology: From Bench to Bedside (Springer Berlin Heidelberg), pp. 39-49
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TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action
Autophagy
2008
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Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression
Cancer Research, Vol. 68, Núm. 6, pp. 1945-1952
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Down-regulation of tissue inhibitor of metalloproteinases-1 in gliomas: a new marker of cannabinoid antitumoral activity?
Neuropharmacology, Vol. 54, Núm. 1, pp. 235-243
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Targeting cannabinoid receptors in brain tumors
Cannabinoids and the Brain (Springer US), pp. 361-374
2007
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Cannabinoids and gliomas
Molecular Neurobiology, Vol. 36, Núm. 1, pp. 60-67
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Cannabinoids induce glioma stem-like cell differentiation and inhibit gliomagenesis
Journal of Biological Chemistry, Vol. 282, Núm. 9, pp. 6854-6862
2006
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Cannabinoid receptors as novel targets for the treatment of melanoma
FASEB Journal, Vol. 20, Núm. 14
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Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes
Cancer Research, Vol. 66, Núm. 13, pp. 6748-6755
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The CB2 cannabinoid receptor signals apoptosis via ceramide-dependent activation of the mitochondrial intrinsic pathway
Experimental Cell Research, Vol. 312, Núm. 11, pp. 2121-2131
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The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells
Cancer Cell, Vol. 9, Núm. 4, pp. 301-312
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p8 Upregulation sensitizes astrocytes to oxidative stress
FEBS Letters, Vol. 580, Núm. 6, pp. 1571-1575
2005
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p38 MAPK is involved in CB2 receptor-induced apoptosis of human leukaemia cells
FEBS Letters, Vol. 579, Núm. 22, pp. 5084-5088
2004
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Ceramide sensitizes astrocytes to oxidative stress: Protective role of cannabinoids
Biochemical Journal, Vol. 380, Núm. 2, pp. 435-440