MANUEL
GUZMÁN PASTOR
Catedrático de universidad
MARÍA DEL MAR
LORENTE PÉREZ
Profesora titular de universidad
Publications by the researcher in collaboration with MARÍA DEL MAR LORENTE PÉREZ (22)
2018
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Optimization of a preclinical therapy of cannabinoids in combination with temozolomide against glioma
Biochemical Pharmacology, Vol. 157, pp. 275-284
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Targeting Glioma Initiating Cells with A combined therapy of cannabinoids and temozolomide
Biochemical Pharmacology, Vol. 157, pp. 266-274
2016
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MicroRNA let-7d is a target of cannabinoid CB
1
receptor and controls cannabinoid signaling
Neuropharmacology, Vol. 108, pp. 345-352
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Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization
Autophagy, Vol. 12, Núm. 11, pp. 2213-2229
2015
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Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation
Cell Death and Differentiation, Vol. 22, Núm. 1, pp. 131-144
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TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling
Molecular and Cellular Oncology, Vol. 2, Núm. 3
2013
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The pseudokinase tribbles homologue-3 plays a crucial role in cannabinoid anticancer action
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Vol. 1831, Núm. 10, pp. 1573-1578
2011
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A combined preclinical therapy of cannabinoids and temozolomide against glioma
Molecular Cancer Therapeutics, Vol. 10, Núm. 1, pp. 90-103
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Detecting autophagy in response to ER stress signals in cancer
Methods in Enzymology (Academic Press Inc.), pp. 297-317
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Stimulation of ALK by the growth factor midkine renders glioma cells resistant to autophagy-mediated cell death
Autophagy, Vol. 7, Núm. 9, pp. 1071-1073
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Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action
Cell Death and Differentiation, Vol. 18, Núm. 6, pp. 959-973
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The orphan G protein-coupled receptor GPR55 promotes cancer cell proliferation via ERK
Oncogene, Vol. 30, Núm. 2, pp. 245-252
2009
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Amphiregulin is a factor for resistance of glioma cells to cannabinoid-induced apoptosis
GLIA, Vol. 57, Núm. 13, pp. 1374-1385
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Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
Journal of Clinical Investigation, Vol. 119, Núm. 5, pp. 1359-1372
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Cannabinoids as potential antitumoral agents in pancreatic cancer
Pancreatology: From Bench to Bedside (Springer Berlin Heidelberg), pp. 39-49
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TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action
Autophagy
2008
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Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression
Cancer Research, Vol. 68, Núm. 6, pp. 1945-1952
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Down-regulation of tissue inhibitor of metalloproteinases-1 in gliomas: a new marker of cannabinoid antitumoral activity?
Neuropharmacology, Vol. 54, Núm. 1, pp. 235-243
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Targeting cannabinoid receptors in brain tumors
Cannabinoids and the Brain (Springer US), pp. 361-374
2007
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Cannabinoids and gliomas
Molecular Neurobiology, Vol. 36, Núm. 1, pp. 60-67