MARÍA LUZ
LÓPEZ RODRÍGUEZ
Investigadora hasta 2022
Jorge
Manzanares Robles
Publicaciones en las que colabora con Jorge Manzanares Robles (8)
2005
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Anxiolytic-like effect of a serotonergic ligand with high affinity for 5-HT1A, 5-HT2A and 5-HT3 receptors
European Journal of Pharmacology, Vol. 511, Núm. 1, pp. 9-19
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Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT1AR agonists with selectivity over α1- adrenoceptors
Journal of Medicinal Chemistry, Vol. 48, Núm. 7, pp. 2548-2558
2003
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Design and synthesis of S-(-)-2-[[4-(napht-1-yl)piperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2- a]pyrazine (CSP-2503) using computational simulation. A 5-HT1A receptor agonist
Bioorganic and Medicinal Chemistry Letters, Vol. 13, Núm. 8, pp. 1429-1432
2001
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Biochemical, electrophysiological and neurohormonal studies with B-20991, a selective 5-HT1A receptor agonist
Pharmacology, Vol. 62, Núm. 4, pp. 234-242
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Synthesis and structure-activity relationships of a new model of arylpiperazines. 5. Study of the physicochemical influence of the pharmacophore on 5-HT1A/α1-adrenergic receptor affinity: Synthesis of a new derivative with mixed 5-HT1A/D2 antagonist properties
Journal of Medicinal Chemistry, Vol. 44, Núm. 2, pp. 186-197
1999
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Design and synthesis of 2-[4-[4-(m-(ethylsulfonamido)-phenyl)piperazin- 1-yl]butyl]-1,3-dioxoperhydropyrrolo[1,2c]imidazole (EF-7412) using neural networks. A selective derivative with mixed 5-HT(1A)/D2 antagonist properties
Bioorganic and Medicinal Chemistry Letters, Vol. 9, Núm. 12, pp. 1679-1682
1998
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Preclinical pharmacology of B-20991, a 5-HT(1A) receptor agonist with anxiolytic activity
European Journal of Pharmacology, Vol. 344, Núm. 2-3, pp. 127-135
1996
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Synthesis and structure-activity relationships of a new model of arylpiperazines. 1. 2-[[4-(o-methoxyphenyl)piperazin-1-yl]methyl]-1,3- dioxoperhydroimidazo[1,5-a]pyridine: A selective 5-HT(1A) receptor agonist
Journal of Medicinal Chemistry, Vol. 39, Núm. 22, pp. 4439-4450