Publicaciones en las que colabora con MARÍA DEL HENAR VÁZQUEZ VILLA (23)

2023

  1. Cancer-Stem-Cell Phenotype-Guided Discovery of a Microbiota-Inspired Synthetic Compound Targeting NPM1 for Leukemia

    JACS Au

2022

  1. 2-(Fluoromethoxy)-4′-(S-methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D1Receptor for Parkinson's Disease

    Journal of Medicinal Chemistry, Vol. 65, Núm. 18, pp. 12256-12272

  2. Discovery of V-0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor toward Oral Treatment for "diabesity"

    Journal of Medicinal Chemistry, Vol. 65, Núm. 7, pp. 5449-5461

  3. New Trends in Aging Drug Discovery

    Biomedicines, Vol. 10, Núm. 8

  4. Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice

    Journal of Medicinal Chemistry, Vol. 65, Núm. 16, pp. 10956-10974

2021

  1. Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery

    Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 5730-5745

2020

  1. A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration

    Journal of Medicinal Chemistry, Vol. 63, Núm. 5, pp. 2372-2390

2019

  1. Allosteric modulators targeting GPCRs

    GPCRs: Structure, Function, and Drug Discovery (Elsevier), pp. 195-241

2017

  1. A Positive Allosteric Modulator of the Serotonin 5-HT2C Receptor for Obesity

    Journal of Medicinal Chemistry, Vol. 60, Núm. 23, pp. 9575-9584

  2. A new serotonin 5-HT 6 receptor antagonist with procognitive activity - Importance of a halogen bond interaction to stabilize the binding

    Scientific Reports, Vol. 7

  3. Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling

    Chemistry - A European Journal, Vol. 23, Núm. 7, pp. 1676-1685

  4. The structural assembly switch of cell division protein FtsZ probed with fluorescent allosteric inhibitors

    Chemical Science, Vol. 8, Núm. 2, pp. 1525-1534

2016

  1. Chemoproteomic approach to explore the target profile of GPCR ligands: Application to 5-HT1A and 5-HT6 receptors

    Chemistry - A European Journal, Vol. 22, Núm. 4, pp. 1313-1321

2015

  1. Effective GTP-replacing FtsZ inhibitors and antibacterial mechanism of action

    ACS Chemical Biology, Vol. 10, Núm. 3, pp. 834-843

  2. New inhibitors of angiogenesis with antitumor activity in vivo

    Journal of Medicinal Chemistry, Vol. 58, Núm. 9, pp. 3757-3766

  3. The status of the lysophosphatidic acid receptor type 1 (LPA<inf>1</inf>R)

    MedChemComm, Vol. 6, Núm. 1, pp. 13-23

2014

  1. Serotonin 5-HT6receptor antagonists for the treatment of cognitive deficiency in Alzheimer's disease

    Journal of Medicinal Chemistry, Vol. 57, Núm. 17, pp. 7160-7181

  2. The extracellular entrance provides selectivity to serotonin 5-HT 7 receptor antagonists with antidepressant-like behavior in vivo

    Journal of Medicinal Chemistry, Vol. 57, Núm. 15, pp. 6879-6884

2013

  1. New serotonin 5-HT1A receptor agonists endowed with antinociceptive activity in vivo

    Journal of Medicinal Chemistry, Vol. 56, Núm. 20, pp. 7851-7861

  2. Synthetic inhibitors of bacterial cell division targeting the GTP-binding site of FtsZ

    ACS Chemical Biology, Vol. 8, Núm. 9, pp. 2072-2083