Publicaciones en colaboración con investigadores/as de Centro de Investigaciones Biológicas (8)

2021

  1. Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery

    Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 5730-5745

2019

  1. A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia

    Journal of Medicinal Chemistry, Vol. 62, Núm. 13, pp. 6035-6046

2017

  1. Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling

    Chemistry - A European Journal, Vol. 23, Núm. 7, pp. 1676-1685

  2. The structural assembly switch of cell division protein FtsZ probed with fluorescent allosteric inhibitors

    Chemical Science, Vol. 8, Núm. 2, pp. 1525-1534

2015

  1. Effective GTP-replacing FtsZ inhibitors and antibacterial mechanism of action

    ACS Chemical Biology, Vol. 10, Núm. 3, pp. 834-843

2013

  1. Synthetic inhibitors of bacterial cell division targeting the GTP-binding site of FtsZ

    ACS Chemical Biology, Vol. 8, Núm. 9, pp. 2072-2083

2012

  1. Structure-activity relationship of a new series of reversible dual monoacylglycerol lipase/fatty acid amide hydrolase inhibitors

    Journal of Medicinal Chemistry, Vol. 55, Núm. 2, pp. 824-836

2010

  1. The antibacterial cell division inhibitor PC190723 is an FtsZ polymer-stabilizing agent that induces filament assembly and condensation

    Journal of Biological Chemistry, Vol. 285, Núm. 19, pp. 14239-14246