GUILLERMO
VELASCO DÍEZ
Profesor titular de universidad
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (22)
2022
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Editorial: Molecular Mechanisms of Autophagy in Cancer
Frontiers in Cell and Developmental Biology
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Safety and Efficacy of Crizotinib in Combination with Temozolomide and Radiotherapy in Patients with Newly Diagnosed Glioblastoma: Phase Ib GEINO 1402 Trial
Cancers, Vol. 14, Núm. 10
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TRIB3 Modulates PPARγ-Mediated Growth Inhibition by Interfering with the MLL Complex in Breast Cancer Cells
International journal of molecular sciences, Vol. 23, Núm. 18
2021
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Cancer Treatment: Preclinical & Clinical
Journal of the National Cancer Institute - Monographs, Vol. 2021, Núm. 58, pp. 107-113
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The pseudokinase TRIB3 negatively regulates the HER2 receptor pathway and is a biomarker of good prognosis in luminal breast cancer
Cancers, Vol. 13, Núm. 21
2020
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Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer
The Journal of experimental medicine, Vol. 217, Núm. 6
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Midkine signaling maintains the self-renewal and tumorigenic capacity of glioma initiating cells
Theranostics, Vol. 10, Núm. 11, pp. 5120-5136
2019
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Inhibiting SUMO1-mediated SUMOylation induces autophagy-mediated cancer cell death and reduces tumour cell invasion via RAC1
Journal of Cell Science, Vol. 132, Núm. 20
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Phosphorylation of FOXO proteins as a key mechanism to regulate their activity
Methods in Molecular Biology (Humana Press Inc.), pp. 51-59
2018
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Optimization of a preclinical therapy of cannabinoids in combination with temozolomide against glioma
Biochemical Pharmacology, Vol. 157, pp. 275-284
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Targeting Glioma Initiating Cells with A combined therapy of cannabinoids and temozolomide
Biochemical Pharmacology, Vol. 157, pp. 266-274
2017
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The cannabinoid receptor CB1 contributes to the development of ectopic lesions in a mouse model of endometriosis
Human Reproduction, Vol. 32, Núm. 1, pp. 175-184
2016
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Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization
Autophagy, Vol. 12, Núm. 11, pp. 2213-2229
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Human Atg8-cardiolipin interactions in mitophagy: Specific properties of LC3B, GABARAPL2 and GABARAP
Autophagy, Vol. 12, Núm. 12, pp. 2386-2403
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The complex relationship of tribbles pseudokinase 1, PML/RARA and C/EBPα in leukemia: Two possible couples but not a trio
Haematologica
2015
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AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation
Nature Cell Biology, Vol. 17, Núm. 1, pp. 20-30
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Autophagy in malignant transformation and cancer progression
EMBO Journal, Vol. 34, Núm. 7, pp. 856-880
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Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death
Journal of Investigative Dermatology, Vol. 135, Núm. 6, pp. 1629-1637
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Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation
Cell Death and Differentiation, Vol. 22, Núm. 1, pp. 131-144
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Oncosuppressive functions of tribbles pseudokinase 3
Biochemical Society Transactions, Vol. 43, pp. 1122-1126