Publicaciones en colaboración con investigadores/as de Hospital Universitario Puerta de Hierro (21)

2018

  1. A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity

    Nature Communications, Vol. 9, Núm. 1

2016

  1. Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains

    Scientific Reports, Vol. 6

2015

  1. Programming controlled adhesion of E. coli to target surfaces, cells, and tumors with synthetic adhesins

    ACS Synthetic Biology, Vol. 4, Núm. 4, pp. 463-473

2013

  1. Basement Membrane-Rich Organoids with Functional Human Blood Vessels Are Permissive Niches for Human Breast Cancer Metastasis

    PLoS ONE, Vol. 8, Núm. 8

  2. Generation and characterization of monospecific and bispecific hexavalent trimerbodies

    mAbs, Vol. 5, Núm. 1, pp. 70-79

  3. Proteasome activator complex PA28 identified as an accessible target in prostate cancer by in vivo selection of human antibodies

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Núm. 34, pp. 13791-13796

2012

  1. Improved stability of multivalent antibodies containing the human collagen XV trimerization domain

    mAbs, Vol. 4, Núm. 2, pp. 226-232

  2. The axonal repellent Slit2 inhibits pericyte migration: Potential implications in angiogenesis

    Experimental Cell Research, Vol. 318, Núm. 4, pp. 371-378

  3. The heterotrimeric laminin coiled-coil domain exerts anti-adhesive effects and induces a pro-invasive phenotype

    PLoS ONE, Vol. 7, Núm. 6

2011

  1. The multicompartmental p32/gClqR as a new target for antibody-based tumor targeting strategies

    Journal of Biological Chemistry, Vol. 286, Núm. 7, pp. 5197-5203

2010

  1. Factory neovessels: Engineered human blood vessels secreting therapeutic proteins as a new drug delivery system

    Gene Therapy, Vol. 17, Núm. 6, pp. 745-751

  2. Multivalent antibodies: When design surpasses evolution

    Trends in Biotechnology, Vol. 28, Núm. 7, pp. 355-362

2009

  1. Differential transplantability of human endothelial cells in colorectal cancer and renal cell carcinoma primary xenografts

    Laboratory Investigation, Vol. 89, Núm. 1, pp. 91-97

  2. In vivo tumor targeting and imaging with engineered trivalent antibody fragments containing collagen-derived sequences

    PLoS ONE, Vol. 4, Núm. 4

  3. Tumor immunotherapy using gene-modified human mesenchymal stem cells loaded into synthetic extracellular matrix scaffolds

    Stem Cells, Vol. 27, Núm. 3, pp. 753-760

2008

  1. Comment on "Production of multivalent protein binders using a self-trimerization collagen-like peptide scaffold"

    FASEB Journal

  2. Long-term in vivo imaging of human angiogenesis: Critical role of bone marrow-derived mesenchymal stem cells for the generation of durable blood vessels

    Microvascular Research, Vol. 75, Núm. 3, pp. 308-314

2007

  1. Inhibition of tumor growth in vivo by in situ secretion of bispecific anti-CEA × anti-CD3 diabodies from lentivirally transduced human lymphocytes

    Cancer Gene Therapy, Vol. 14, Núm. 4, pp. 380-388

2006

  1. Enhanced antiangiogenic therapy with antibody-collagen XVIII NC1 domain fusion proteins engineered to exploit matrix remodeling events

    International Journal of Cancer, Vol. 119, Núm. 2, pp. 455-462

  2. Enhancement of DNA vaccine potency through linkage of antigen to filamentous bacteriophage coat protein III domain I

    Immunology, Vol. 117, Núm. 4, pp. 502-506