Publications by the researcher in collaboration with Antonio García García (23)

2020

  1. Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties

    Drug Development Research, Vol. 81, Núm. 3, pp. 283-294

  2. New Nrf2-inducer compound ITH12674 slows the progression of retinitis pigmentosa in the mouse model rd10

    Cellular Physiology and Biochemistry, Vol. 54, Núm. 1, pp. 142-159

2017

  1. Addition to "ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia"

    ACS chemical neuroscience, Vol. 8, Núm. 1, pp. 210

  2. ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia

    ACS Chemical Neuroscience, Vol. 8, Núm. 1, pp. 67-81

  3. Novel sulfoglycolipid IG20 causes neuroprotection by activating the phase II antioxidant response in rat hippocampal slices

    Neuropharmacology, Vol. 116, pp. 110-121

2015

  1. Melatonin-sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a 'drug-prodrug' mechanism of action

    British Journal of Pharmacology, Vol. 172, Núm. 7, pp. 1807-1821

2013

  1. Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia

    Neuropharmacology, Vol. 67, pp. 403-411

  2. Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease

    Medicinal Research Reviews, Vol. 33, Núm. 1, pp. 139-189

2012

  1. Benzothiazepine CGP37157 and its isosteric 2′-ethyl analogue provide neuroprotection and block cell calcium entry

    ACS Chemical Neuroscience, Vol. 3, Núm. 7, pp. 519-529

2011

  1. Effects of novel tacripyrines ITH12117 and ITH12118 on rat vas deferens contractions, calcium transients and cholinesterase activity

    European Journal of Pharmacology, Vol. 660, Núm. 2-3, pp. 411-419

  2. N-Acylaminophenothiazines: Neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 6, pp. 2224-2235

2010

  1. Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives

    Journal of Medicinal Chemistry, Vol. 53, Núm. 14, pp. 5129-5143

2009

  1. Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease

    Journal of Medicinal Chemistry, Vol. 52, Núm. 9, pp. 2724-2732

2008

  1. New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 16, pp. 7759-7769

  2. Synthesis of 6-amino-1,4-dihydropyridines that prevent calcium overload and neuronal death

    European Journal of Medicinal Chemistry, Vol. 43, Núm. 3, pp. 668-674

2006

  1. New multipotent tetracyclic tacrines with neuroprotective activity

    Bioorganic and Medicinal Chemistry, Vol. 14, Núm. 24, pp. 8176-8185

  2. Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease

    Journal of Medicinal Chemistry, Vol. 49, Núm. 26, pp. 7607-7610

  3. Synthesis and biological evaluation of new 4H-pyrano[2,3-b]quinoline derivatives that block acetylcholinesterase and cell calcium signals, and cause neuroprotection against calcium overload and free radicals

    European Journal of Medicinal Chemistry, Vol. 41, Núm. 12, pp. 1464-1469

  4. Unexpected results in the Friedländer reaction of 4-aryl-7,7-dimethyl- 5-oxo-5,6,7,8-tetrahydro-4H-[1]benzopyran-3-carbonitriles

    Journal of Chemical Research, pp. 536-538

2005

  1. 1,6-C-H and 1,5-O-Si insertion reactions of alkylidenecarbene derivatives of monosaccharides

    Journal of Carbohydrate Chemistry, Vol. 24, Núm. 4-6, pp. 369-377