Publicaciones en las que colabora con Manuela García López (40)

2024

  1. Discovery of a potent melatonin-based inhibitor of quinone reductase-2 with neuroprotective and neurogenic properties

    European Journal of Medicinal Chemistry, Vol. 277

  2. Innovative pathological network-based multitarget approaches for Alzheimer's disease treatment

    Medicinal Research Reviews, Vol. 44, Núm. 6, pp. 2367-2419

2023

  1. KEAP1-NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

    Medicinal Research Reviews, Vol. 43, Núm. 1, pp. 237-287

2022

  1. Resveratrol-Based MTDLs to Stimulate Defensive and Regenerative Pathways and Block Early Events in Neurodegenerative Cascades

    Journal of Medicinal Chemistry, Vol. 65, Núm. 6, pp. 4727-4751

2020

  1. Antioxidant, anti-inflammatory and neuroprotective profiles of novel 1,4-dihydropyridine derivatives for the treatment of alzheimer’s disease

    Antioxidants, Vol. 9, Núm. 8, pp. 1-20

  2. Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization

    Pharmacological Research, Vol. 152

  3. Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties

    European Journal of Medicinal Chemistry, Vol. 190

2019

  1. Pharmacological doses of melatonin impede cognitive decline in tau-related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux

    Journal of Pineal Research, Vol. 67, Núm. 1

2018

  1. The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and glucose deprivation, Ca 2+ dysregulation, and mitochondrial abnormalities

    Journal of Neurochemistry, Vol. 145, Núm. 2, pp. 170-182

  2. Transcription factor NRF2 as a therapeutic target for chronic diseases: A systems medicine approach

    Pharmacological Reviews, Vol. 70, Núm. 2, pp. 348-383

2017

  1. Addition to "ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia"

    ACS chemical neuroscience, Vol. 8, Núm. 1, pp. 210

  2. ConBr, A Lectin Purified from the Seeds of Canavalia brasiliensis, Protects Against Ischemia in Organotypic Culture of Rat Hippocampus: Potential Implication of Voltage-Gated Calcium Channels

    Neurochemical Research, Vol. 42, Núm. 2, pp. 347-359

  3. Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease

    Scientific Reports, Vol. 7

  4. Enzymatic and solid-phase synthesis of new donepezil-based L- and D-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia

    European Journal of Medicinal Chemistry, Vol. 130, pp. 60-72

  5. ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia

    ACS Chemical Neuroscience, Vol. 8, Núm. 1, pp. 67-81

  6. Novel sulfoglycolipid IG20 causes neuroprotection by activating the phase II antioxidant response in rat hippocampal slices

    Neuropharmacology, Vol. 116, pp. 110-121

  7. Saffron (Crocus sativus) intake provides nutritional preconditioning against myocardial ischemia–reperfusion injury in Wild Type and ApoE(−/−) mice: Involvement of Nrf2 activation

    Nutrition, Metabolism and Cardiovascular Diseases, Vol. 27, Núm. 10, pp. 919-929

2016

  1. Subthreshold Concentrations of Melatonin and Galantamine Improves Pathological AD-Hallmarks in Hippocampal Organotypic Cultures

    Molecular Neurobiology, Vol. 53, Núm. 5, pp. 3338-3348

2015

  1. Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase i induction

    Biochemical Pharmacology, Vol. 97, Núm. 4, pp. 473-481

  2. Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection

    Biochemical Pharmacology, Vol. 97, Núm. 4, pp. 463-472